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In the title compound, C20H23NO, the cycloheptanone ring adopts a twist-chair conformation, with the aminomethyl substituent in an equatorial position. The relative configuration of the two stereocenters is R,R. In the crystal, molecules are linked by N—HO hydrogen bonds into chains along [100].
organic compounds
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The title compound, C19H14F3NO2, crystallizes in the keto–amine tautomeric form, with a strong intramolecular N—HO hydrogen bond. The molecule is almost planar; the dihedral angle between the naphthalene ring system and the benzene ring is 4.60 (7)°. In the crystal, molecules are linked into chains along the c axis by C—HO hydrogen bonds. The F atoms of the trifluoromethyl group are disordered over two positions with refined site occupancies of 0.668 (9) and 0.332 (9).
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In the title compound, C18H15N5O2S, a weak intramolecular C—HS hydrogen bond results in a small dihedral angle of 3.71 (9)° between the methylphenyl and triazole rings, which, in turn, form dihedral angles of 80.09 (8) and 77.32 (8)°, respectively, with the benzoxazolone mean plane. In the crystal, N—HO hydrogen bonds link molecules into chains along [001], and weak C—HN hydrogen bonds and π–π interactions between the five- and six-membered rings [centroid–centroid distances = 3.5074 (11) and 3.616 (1) Å] consolidate the crystal packing.
organic compounds
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The title compound, C18H11BrF3NO2, crystallizes in the phenol–imine tautomeric form, with a strong intramolecular O—HN hydrogen bond. The dihedral angle between the naphthalene ring system and the benzene ring is 28.54 (10)°.
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In the title compound, C19H12Cl2N2O4, the imine bond length of 1.257 (6) Å is typical of a double bond. The dihedral angle between the para-nitro benzene ring and the central benzene ring is 12.06 (3)° and that between the central benzene and the para-chloro benzene ring is 73.81 (2)°. An intramolecular O—HN hydrogen bond generates an S(6) ring motif. In the crystal, molecules are linked together by two pairs of C—HO interactions (to the same O atom acceptor), forming inversion dimers. A short ClCl contact [3.232 (4) Å] is observed.
organic compounds
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In the title compound, C16H18ClN3O, the cyclohexane ring adopts a distorted chair conformation. In the crystal, pairs of molecules are linked by N—HO hydrogen bonds into inversion dimers, forming R22(10) ring motifs. These dimers are connected through C—HN hydrogen bonds into chains along the a axis, forming layers parallel to (101).
organic compounds
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In the title compound, C24H26FN3O, the cyclohexane ring adopts a chair conformation; the propyl substituent is in an equatorial orientation and the bond-angle sum at the C atom bonded to the carbohydrazide N atom is 360.0°. The dihedral angle between the 1H-indole ring system and the phenyl ring is 82.77 (13)°. A weak intramolecular C—Hπ contact occurs. In the crystal, pairs of molecules related by a crystallographic twofold axis are linked by bifurcated N—H(O,N) hydrogen bonds; a C—HO interaction occurs between the same pair. The dimers are linked by C—HF and C—Hπ interactions, generating a three-dimensional network.
organic compounds
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The title compound, C22H22FN3O, crystallized with two independent molecules (A and B) in the asymmetric unit; these are linked by a pair of N—HO hydrogen bonds, forming a pseudo-centrosymmetric dimer with an R22(10) motif. In addition, a number of C—Hπ interactions are also observed. The 1H-indole ring systems in molecules A and B are essentially planar [maximum deviations of 0.019 (2) and 0.014 (2) Å, respectively] and make dihedral angles of 77.64 (10) and 69.50 (9)°, respectively, with thephenyl rings.
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In the title compound, C24H24FN3O2S, the 1,3-thiazolidine ring adopts an envelope conformation with the S atom as the flap, while the cyclohexane ring is in a chair conformation. In the crystal, molecules are linked by N—HO and C—HF hydrogen bonds, forming a three-dimensional network. The unit cell contains six voids of 57 Å3, but the residual electron density (highest peak = 0.23 e Å−3 and deepest hole = −0.19 e Å−3) in the difference Fourier map suggests no solvent molecule occupies this void.
organic compounds
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The title compound, C23H24FN3O, crystallizes with two independent molecules (I and II) in the asymmetric unit. These pairs of molecules are linked to each other as N—HO dimers with an R22(10) motif. Furthermore, the crystal structure also exhibits C—Hπ interactions. The atoms of the ethyl group in molecule I are disordered over two sites with an occupancy ratio of 0.817 (6):0.183 (6).
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(3aR,6S,7aR)-7a-Chloro-2-[(4-nitrophenyl)sulfonyl]-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole
In the title compound, C14H13ClN2O5S, the chlorine-substituted tetrahydrofuran ring adopts a twist conformation and the other tetrahydrofuran ring an envelope conformation with the O atom as the flap. The pyrrolidine ring adopts a twist conformation. In the crystal, C—HO hydrogen bonds link the molecules into zigzag chains running along the b-axis direction.
organic compounds
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The title compound, C16H23N3O3, contains two morpholine rings, each of which adopts a chair conformation. The molecular conformation is stabilized by an intramolecular O—HN hydrogen bond, leading to a S(6) ring. In the crystal, molecules are linked into zigzag chains along the c-axis direction by C—HO and C—Hπ interactions.
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In the title compound, C20H18N4O3, the dihedral angles between the central benzene ring and the 1H-1,2,3-triazole ring and the fused benzene ring are 65.34 (19) and 3.64 (18)°, respectively. The dioxole ring adopts a shallow envelope conformation, with the methylene C atom displaced by 0.156 (5) Å from the other four atoms (r.m.s. deviation = 0.007Å). In the crystal, the molecules are linked by C—HO and C—HN hydrogen bonds, generating a three-dimensional network.
organic compounds
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In the title compound, C15H15ClN2O5S, the tetrahydrofuran ring adopts an envelope conformation with the O atom as the flap. The pyrrolidine ring adopts an envelope conformation with the chlorine-substituted C atom as the flap. In the crystal, two types of C—HO hydrogen bonds generate R22(20) and R44(26) rings, with adjacent rings running parallel to ac plane. Further C—HO hydrogen bonds form a C(6) chain, linking the molecules in the b-axis direction.