Preliminary joint X-ray and neutron protein crystallographic studies of ecDHFR complexed with folate and NADP⁺

Q. Wan, A. Y. Kovalevsky, M. A. Wilson, B. C. Bennett, P. Langan and C. Dealwis

A 2.0 Å resolution neutron data set and a 1.6 Å resolution X-ray data set were collected for joint X-ray/neutron refinement of the ecDHFR-folate-NADP⁺ complex in order to study the reaction mechanism of dihydrofolate reductase.

Keywords: Escherichia coli; dihydrofolate reductase; protonation state.

Read article Similar articles

Format		BIBTeX
		EndNote
		RefMan
		Refer
		Medline
		CIF
		SGML
		Text
		Plain Text

Format		BIBTeX
		EndNote
		RefMan
		Refer
		Medline
		CIF
		SGML
		Text
		Plain Text

Search IUCr Journals		doi		Advanced search
Author		volume	page

Preliminary joint X-ray and neutron protein crystallographic studies of ecDHFR complexed with folate and NADP+

Preliminary joint X-ray and neutron protein crystallographic studies of ecDHFR complexed with folate and NADP⁺