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Proliferating cell nuclear antigen (PCNA) plays essential roles in DNA replication, DNA repair, cell-cycle regulation and chromatin metabolism. The PCNA from Drosophila melanogaster (DmPCNA) has been purified and crystallized.

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The conserved protein MO25 activates STE20 family kinases. The crystal structure of zebrafish MO25 is reported, which is similar to that of human MO25.
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