Time-of-flight Bragg scattering from aligned stacks of lipid bilayers using the Liquids Reflectometer at the Spallation Neutron Source

A procedure to use time-of-flight neutron diffraction at the Spallation Neutron Source to exploit structures of aligned stacks of lipid bilayers is reported. The method was verified by two well known lipid bilayers and then applied to elucidate the impact imparted by the antimicrobial peptide alamethicin on membranes with and without cholesterol.