research papers
7-Cyclopropyl-2′-deoxytubercidin, a carbocyclic side-chain derivative of 7-deaza-2′-deoxyadenosine, exhibits an anti glycosylic bond conformation.The furanose group shows a twisted C1′-exo sugar pucker (S-type), the orientation of the exocyclic C4′—C5′ bond is -ap (trans) and the cyclopropyl substituent points away from the nucleobase (anti orientation). Within the three-dimensional extended crystal structure, the individual molecules are stacked and arranged into layers, which are highly ordered and stabilized by hydrogen bonding.