Structures of Ser205 mutant plasmepsin II from Plasmodium falciparum at 1.8 Å in complex with the inhibitors rs367 and rs370

Two 1.8 Å resolution crystal structures of the Ser205 mutant plasmepsin II from P. falciparum in complex with two Phe–Leu core inhibitors that incorporate tetrahedral transition-state mimetic hydroxypropylamine are described.