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The title compound, C15H16NS+·C2H3O2-, has been crystallized as both a pure enantio­mer (1S,5R) and a racemate. The racemate crystallizes in the space group Cc, with mol­ecules of opposite handedness related to each other by the action of the c-glide. The enantio­mer is essentially isostructural with the racemate, except that the glide symmetry is violated by inter­change of CH and CH2 groups within the seven-membered ring. The space-group symmetry is reduced to P1 with two mol­ecules in the asymmetric unit. The enantio­mer structure shows disorder of the thio­phene ring for one of the mol­ecules in the asymmetric unit. The major component of the disorder has the thio­phene ring in the same position as in the racemate, but generates a higher-energy mol­ecular conformation. The minor disorder component has different inter­molecular inter­actions but retains a more stable mol­ecular conformation.

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The title compound, C18H19Cl2NO4·C6H12N2·H2O, is a co­crystal hydrate containing the active pharmaceutical ingredient felodipine and diaza­bicyclo­[2.2.2]octane (DABCO). The DABCO and water mol­ecules are linked through O-H...N hydrogen bonds into chains around 21 screw axes, while the felodipine mol­ecules form N-H...O hydrogen bonds to the water mol­ecules. The felodipine mol­ecules adopt centrosymmetric back-to-back arrangements that are similar to those present in all of its four reported polymorphs. The dichloro­phenyl rings also form [pi]-stacking inter­actions. The inclusion of water mol­ecules in the cocrystal, rather than formation of N-H...N hydrogen bonds between felodipine and DABCO, may be associated with steric hindrance that would arise between DABCO and the methyl groups of felodipine if they were directly involved in hydrogen bonding.
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