The structure of augmenter of liver regeneration crystallized in the presence of 50 mM CdCl₂ reveals a novel Cd₂Cl₄O₆ cluster that aids in crystal packing

The 2.4 Å crystal structure of the protein augmenter of liver regeneration (hsALR) containing a 14-residue histidine purification tag has been determined by Cd-SAD. The structure reveals a tetramer (two hsALR homodimers) bridged by a novel Cd₂Cl₄O₆ cluster that produces a crystal packing environment that can better accommodate the N-terminal purification tag.