Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates

The crystal structure of human PTPRQ and the following kinetic data provide the explanation for its dephosphosphorylating activity towards phosphatidyl inositides.

Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes

The crystal structure of the SOCS2-elongin BC-Cul5(1-386) complex explains the specificity of Cul2 and Cul5 for elongin BC and their preferential association with Cul2 or Cul5 box-containing proteins.