Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates

K. R. Yu, Y. J. Kim, S.-K. Jung, B. Ku, H. Park, S. Y. Cho, H. Jung, S. J. Chung, K. H. Bae, S. C. Lee, B. Y. Kim, R. L. Erikson, S. E. Ryu and S. J. Kim

The crystal structure of human PTPRQ and the following kinetic data provide the explanation for its dephosphosphorylating activity towards phosphatidyl inositides.

Keywords: PTP receptor type Q; protein tyrosine phosphatases.

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