10-(4-Chloro­phen­yl)-14a-hy­droxy-12-methyl-8,9,9a,10,12,13,14,14a-octa­hydro-5H-10a,14-methano­indeno­[2′,1′:4,5]azepino[3,4-b]pyrrolizine-5,15(7H,11H)-dione

The asymmetric unit of the title compound, C₂₆H₂₅ClN₂O₃, contains two independent mol­ecules (A and B). The conformation of the two mol­ecules differs essentially in the dihedral angle involving the two benzene rings. They are inclined to one another by 52.47 (10) in A and by 31.75 (11)° in B. In both mol­ecules, the six-membered piperidin-3-one rings have chair conformations. In mol­ecule A, all four five-membered rings have twist conformations. In mol­ecule B, only three of the four five-membered rings have twist conformations. The fourth, of the inden-1-one moiety, has an envelope conformation with the spiro C atom, bonded to the N atom of the pyrrolidine ring, as the flap. A weak intra­molecular O—H...N hydrogen bond occurs in each independent mol­ecule while a C—H...O inter­action is also observed in mol­ecule A. In the crystal, pairs of O—H...O hydrogen bonds link the mol­ecules, forming inversion dimers with graph-set motif R₂²(12). These dimers are further inter­connected by C—H...O and C—H...π inter­actions, forming a three-dimensional network.