metal-organic compounds
Open access
The title compound, [Co(C30H23O2P2)(C3H9P)2], was synthesized by the addition of a Co(PMe3)4 solution to (PPh2O)2C6H4. The CoI atom displays a trigonal-bipyramidal geometry with the two P atoms of the `PCP' pincer ligand and the P atom of one of the trimethyl phosphine ligands forming the basal plane, whereas the metalated C atom and the P atom of the second phospine ligand occupy the apical sites. The Co-C distance is 1.961 (2) Å and the C-Co-P angle is 171.96 (6)°.
organic compounds
Open access
Prasugrel {systematic name: 5-[(2-cyclopropylcarbonyl)(2-fluorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate}, C20H20FNO3S, is a new third-generation thienopyridine which was recently approved for clinical use as a more potent blocker of the platelet P2Y12 receptor than clopidogrel, which was previously used for this purpose. The molecule features a tetrahydrothienopyridine system with the tetrahydropyridine ring showing a half-chair conformation; the dihedral angle formed by the the planes of the benzene and thiophene rings is 83.17 (3)°.