[2,6-Bis(diphenyl­phosphino­oxy)phen­yl]bis­(trimethyl­phosphine)cobalt(I)

The title compound, [Co(C₃₀H₂₃O₂P₂)(C₃H₉P)₂], was synthesized by the addition of a Co(PMe₃)₄ solution to (PPh₂O)₂C₆H₄. The Co^I atom displays a trigonal-bipyramidal geometry with the two P atoms of the `PCP' pincer ligand and the P atom of one of the trimethyl phosphine ligands forming the basal plane, whereas the metalated C atom and the P atom of the second phospine ligand occupy the apical sites. The Co-C distance is 1.961 (2) Å and the C-Co-P angle is 171.96 (6)°.

Prasugrel, a new medicine for preventing blockages in the arteries

Prasugrel {systematic name: 5-[(2-cyclo­propyl­carbon­yl)(2-fluoro­phen­yl)meth­yl]-4,5,6,7-tetra­hydro­thieno[3,2-c]pyridin-2-yl acetate}, C₂₀H₂₀FNO₃S, is a new third-generation thienopyridine which was recently approved for clinical use as a more potent blocker of the platelet P2Y₁₂ receptor than clopidogrel, which was previously used for this purpose. The mol­ecule features a tetra­hydro­thienopyridine system with the tetra­hydro­pyridine ring showing a half-chair conformation; the dihedral angle formed by the the planes of the benzene and thio­phene rings is 83.17 (3)°.