organic compounds
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In the title compound, C32H28F2N2O2, the tetrahydropyridine ring adopts a distorted boat conformation. The two fluorophenyl groups are attached to the tetrahydropyridine ring in a trans orientation. The dihedral angle between the planes of the fluoro-substituted rings is 57.0 (1)°. The amino group and carbonyl O atom are involved in intramolecular hydrogen bonding. In the crystal, weak C—HO, C—HF and C—Hπ interactions link the molecules into columns along [010].
organic compounds
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In the title molecule, C31H24F4N2O2, the tetrahydropyridine ring adopts a distorted boat conformation. An intramolecular N—HO hydrogen bond is formed by the amino group and ccarboxyl C=O atom. The crystal structure features weak C—HF and C—HO interactions.
organic compounds
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In the title molecule, C34H32Cl2N2O2, the tetrahydropyridine ring adopts a distorted boat conformation and both 4-chlorophenyl substituents are in axial positions. An intramolecular N—HO hydrogen bond is formed by the amino group and carbonyl O atom. In the crystal, weak C—HCl interactions link the molecules into chains along [010].
organic compounds
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In the title compound, C13H12O5, the mean plane of the 2H-chromene ring system (r.m.s deviation = 0.026 Å) forms a dihedral angle of 81.71 (6)° with the mean plane of ethyl 2-hydroxyacetate moiety (r.m.s deviation = 0.034 Å). In the crystal, C—HO hydrogen bonds result in the formation of zigzag layers parallel to the bc plane.
organic compounds
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In the title compound, C14H17N3O2, the mean plane of the 1,8-naphthyridine ring system (r.m.s deviation = 0.020 Å) forms a dihedral angle of 23.4 (1)° with the acetamide moiety (r.m.s deviation = 0.001 Å). The molecular structure is stabilized by an intramolecular O—HN hydrogen bond, which generates an S(5) ring motif. In the crystal, molecules are linked into inversion dimers by pairs of N—HO hydrogen bonds, generating 18-membered R22(18) ring motifs.
organic compounds
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In the title compound, C32H26Cl2F2N2O2, the tetrahydropyridine ring adopts a distorted boat conformation. The chlorophenyl rings are inclined to one another by 55.2 (1)°, while for the fluorophenyl rings the dihedral angle is 80.7 (1)°. The amino group and carbonyl O atom are involved in an intramolecular N—HO hydrogen bond. In the crystal, weak C—HO, C—HF and C—HCl interactions link the molecules into a three-dimensional network.
organic compounds
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The title compound, C19H19N5O5·3.5H2O, crystallizes with 3.5 molecules of water in the asymmetric unit, one of which lies on a mirror plane. One of the water molecules links the molecules, forming centrosymmetric dimers. These dimers are then linked through further N—HO and O—HO hydrogen bonding, leading to the observed three-dimensional structure.