Cinnamic acid hydrogen bonds to isoniazid and N′-(propan-2-yl­idene)isonicotinohydrazide, an in situ reaction product of isoniazid and acetone

A new polymorph of the cinnamic acid–isoniazid cocrystal is characterized by hydrogen-bonded tetra­meric arrangements of two mol­ecules of isoniazid and two of cinnamic acid. Possible modification of the hydrogen bonding was investigated by changing the hydrazide group of isoniazid by an in situ reaction with acetone and cocrystallization with cinnamic acid.