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The crystal structure of GNA1162 from N. meningitidis has been determined at 1.89 Å resolution and its structural analysis provides important information on its function.

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The kinase domain of SAD-1 from C. elegans has been overexpressed in Escherichia coli BL21 (DE3) cells and purified to homogeneity using nickel–nitrilotriacetic acid metal-affinity, ion-exchange and gel-filtration chromatography. Diffraction-quality crystals were grown using the sitting-drop vapour-diffusion technique.
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