Crystallization and preliminary diffraction studies of SFC-1, a carbapenemase conferring antibiotic resistance

The SFC-1 gene from S. fonticola was cloned and SFC-1 was expressed, purified and crystallized. X-ray diffraction data were collected from an SFC-1 crystal to 1.6 Å resolution.

Expression, crystallization and preliminary X-ray crystallographic analysis of cystathionine γ-synthase (XometB) from Xanthomonas oryzae pv. oryzae

Cystathionine γ-synthase (CGS) catalyzes the γ-replacement reaction of O-succinylhomoserine and L-cysteine to form L-cystathionine and succinate. As an antibacterial drug target, CGS from X. oryzae pv. oryzae (XometB) was cloned, purified and crystallized, and a preliminary X-ray crystallography analysis of the XometB crystal was performed.