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The title compound, C25H26Cl2FN3O4S, contains two bio-active moieties (thio­barbituric acid and fluoro­quinolone). In the crystal, mol­ecules are linked via C—H...O and C—H...F hydrogen bonds, forming two-dimensional slab-like networks lying parallel to the bc plane. The benzene ring substituted by F and Cl atoms and the 4-chloro­butyl group seem to be partly disordered, however attempts to model the disorder were unsuccessful.
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