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The title compound, C21H26NO4+·Br, also known as R-methyl­naltrexone (MNTX) bromide, is a selective peripher­ally acting μ-opioid receptor antagonist with a oroxymorphone skeleton, synthesized by hydroxyl protection, N-methyl­ation, deprotection and anion exchange of naltrexone. It comprises a five-ring system A/B/C/D/E. Rings C and E adopt distorted chair conformations, whereas ring D is in half-chair conformation. The C/E ring junctions are trans fused. The dihedral angle between rings D and E is 82.3 (1)°, while the dihedral angles between the planes of rings C and A, and rings D and E are respectively 81.7 (1), 75.9 (1) and 12.2 (1)°. In the crystal, mol­ecules are linked by O—H...Br hydrogen bonds.

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In the title compound, C8H5NOS2, the non-H atoms are approximately coplanar [maxium deviation = 0.060 (3) Å]. The dihedral angle between the least-squares planes of the pyridine and 1,3-dithiol-2-one rings is 5.96 (17)°. The crystal packing is stabilized by weak inter­molecular C—H...O hydrogen bonds and by an S...S close contact [3.510 (5) Å].

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The asymmetric unit of the title compound, [CdCl2(C7H10N2O2S)2], contains two complex molecules with similar configurations. The CdII atoms are each six-coordinated by two thiazole N and two carbonyl O atoms from the 2-(2-amino-1,3-thiazol-4-yl)acetate ligand, and by two Cl anions in a distorted octa­hedral geometry. In the crystal, intra- and inter­molecular N—H...Cl hydrogen bonds create parallel chains along [1-10]. C—H...Cl inter­actions also occur.

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The title compound, C6H7O2S3+·BF4, consists of a planar 2-thioxo-1,3-dithiol-4,5-yl unit [maximum deviation from the ring plane = 0.020 (3) Å], with an ethyl­enedi­oxy group fused at the 4,5-positions; the ethyl­enedi­oxy C atoms are disordered over two positions with site-occupancy factors of 0.5. The 1,4-dioxine ring has a twist-chair conformation. Weak cation–anion S...F inter­actions [3.022 (4)–3.095 (4) Å] and an S...O [3.247 (4) Å] inter­action are present.

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The complete mol­ecule of the title compound, C16H14N4, is generated by crystallographic inversion symmetry. In the crystal, mol­ecules are linked by N—H...N hydrogen bonds, generating (001) sheets. Weak aromatic π–π stacking inter­actions [centroid–centroid distances = 3.7383 (13) and 3.7935 (14) Å] are also observed.
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