Structure, recombinant expression and mutagenesis studies of the catalase with oxidase activity from Scytalidium thermophilum

The catalytic and oxidative activities of the catalase from Scytalidium thermophilum are likely to be associated with the same haem active centre. The secondary oxidase activity may be a general feature of monofunctional catalases in the absence of hydrogen peroxide. This bifunctionality may provide some advantages for industry if the oxidase activity can be enhanced through engineering or directed evolution.