The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding

The crystal structures of the N-terminal tandem RRM domains of HuR are reported in RNA-free and RNA-bound forms.

Structure of the JmjC-domain-containing protein JMJD5

The crystal structure of JMJD5^176-C revealed that three residues with large side chains located at the entrance to the substrate-binding pocket abolish the histone demethylase activity of this fragment of JMJD5. The structural similarity of JMJD5 to FIH suggested that human JMJD5 might function as a protein hydroxylase.