The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding

The crystal structures of the N-terminal tandem RRM domains of HuR are reported in RNA-free and RNA-bound forms.

Structures of enzyme–intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2

Structures of yeast Nit2 in complex with α-ketoglutarate and with oxaloacetate revealed the molecular-recognition mechanism of the enzyme for the first time, while that of the C169S mutant of yeast Nit2 showed a new ligand located in the catalytic cavity.

Structural insights into the role of the Chl4-Iml3 complex in kinetochore assembly

The Iml3 protein adopts a novel structure to dimerize with the Chl4 in kinetochore assembly.