Acta Crystallographica Section F
Acta Crystallographica
Section F
STRUCTURAL BIOLOGY COMMUNICATIONS
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Acta Cryst.
(2012).
F
68
,
860-866
https://doi.org/10.1107/S1744309112027108
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Download citation
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Flexibility of the P-loop of Pim-1 kinase: observation of a novel conformation induced by interaction with an inhibitor
L. J. Parker
,
H. Watanabe
,
K. Tsuganezawa
,
Y. Tomabechi
,
N. Handa
,
M. Shirouzu
,
H. Yuki
,
T. Honma
,
N. Ogawa
,
T. Nagano
,
S. Yokoyama
and
A. Tanaka
The structures of Pim1 kinase in complex with
in silico
screening hits and several subsequently optimized inhibitors, are reported.
Keywords:
Pim-1
;
kinases
;
inhibitors
.
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