crystallization papers
The single-stranded DNA-binding protein from M. tuberculosis has been crystallized in a trigonal form and an orthorhombic form. A mercury derivative of the trigonal crystals has been prepared.
Keywords: single-stranded DNA-binding protein.
research papers
The resolution and the definition of the structure of garlic lectin could be improved by re-refinement using reprocessed data employing different program packages. The re-refined structure, amongst other things, leads to a better identification of residues at the variable locations in the sequence and hence of isolectins.
research papers
The structure analysis of high-salt crystals of oxy- and deoxyhaemoglobin at different levels of environmental humidity and solvent content appears to indicate that the deoxy form can access an ensemble of related T states.
research papers
A comparative study involving monoclinic lysozyme crystals grown in the presence of sucrose, trehalose, sorbitol and glycerol suggests that the stabilizing additives have no significant effect on the structure of the enzyme and the organization of the ordered water molecules around it.
research papers
A comparative study involving the structures reported here and similar known structures show that the mobility of the UDG molecule consists of the rigid-body movement of the two domains that make up the molecule and the flexibility within the domains. DNA binding leads to domain closure, while association with the proteinaceous inhibitor does not.
Keywords: uracil DNA glycosylase.