Crystal structure of equine apolactoferrin at 303 K providing further evidence of closed conformations of N and C lobes

The structure of equine apolactoferrin has been determined at 303 K. Both N and C lobes have been found in the closed conformations similar to those observed in various metal-saturated lactoferrin forms and in apolactoferrin at 277 K.

Design of specific peptide inhibitors of phospholipase A₂: structure of a complex formed between Russell's viper phospholipase A₂ and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS)

The structure of the complex formed between Russell's viper phospholipase A₂ and a designed peptide LAIYS has been determined at 2.0 Å resolution. The peptide binds to phospholipase A₂ specifically and fills the hydrophobic channel completely.