10′′-(4-Methoxy­benzyl­idene)-5′′,4′-bis(4-methoxy­phen­yl)-1′-meth­yl-2,3,2′′,3′′,7′′,8′′,9′′,10′′-octa­hydro-1H,5′′H,6′′H-indole-3-spiro-2′-pyrrolidine-3′-spiro-2′′-cyclo­hepteno[1,2-d]thia­zolo[3,2-a]pyrimidine-2,3′′-dione

The title compound, C₄₄H₄₂N₄O₅S, was synthesized by the inter­molecular [3+2] cyclo­addition of an azomethine ylide, derived from isatin and sarcosine by a deca­rboxylative route, and 5-(4-methoxyphen­yl-10-(4-methoxy)benzyl­idene-2-(4-methoxy)benzyl­idene-2,3,6,7,8,9-hexa­hydro-5H,10H-cyclohepta­[1,2-d]thia­zolo[3,2-a]pyrimidin-3-one. In the mol­ecule, the two spiro junctions link a planar 2-oxindole ring, a pyrrolidine ring in an envelope conformation and a 10-(aryl­methyl­ene)hexa­hydro­cyclo­hepta­[1,2-d]thia­zolo[3,2-a]pyrimidin-3-one ring. The packing of the mol­ecules in the crystal structure is mainly governed by N—H...N hydrogen bonds.

3-(4-Chloro­phen­yl)-5-methyl-2-propyl­amino-8,9,10,11-tetra­hydro-2-benzothieno­[2′,3′;2,3]­pyrido[4,5-d]pyrimidin-4(3H)-one

The asymmetric unit of the title compound, C₂₃H₂₃ClN₄OS, contains two crystallographically independent mol­ecules in which the orientations of the propyl­amine group and chloro­phenyl rings with respect to the fused ring system are different. The terminal cyclo­hexene ring adopts a half-chair conformation. The crystal packing is stabilized by N—H...O, N—H...N and C—H...O hydrogen bonds and π–π inter­actions.