Crystallization and preliminary crystallographic investigation of a low-pH native insulin monomer with flexible behaviour

Porcine insulin has been crystallized as a monomer in the presence of 20% acetic acid. X-ray data has been collected to 1.6 Å resolution.

The structure of S100A12 in a hexameric form and its proposed role in receptor signalling

The structure of a hexameric form of S100A12, a member of the S100 family of proteins, has been solved at 2.7 Å resolution. The results suggest a functional significance for the hexamer.

Jolly SAD

Numerous examples show that with accurate diffraction data SAD phasing leads to a rapid solution of macromolecular crystal structures.