Structure of a Cys25→Ser mutant of human cathepsin S

The preparation and crystal structure determination of the active-site Cys25→Ser mutant of human cathepsin S at 2.2 Å resolution is described. This structure clearly defines both the catalytic triad and the substrate-binding region.

Crystallization of the AAA domain of the ATP-­dependent protease FtsH of Escherichia coli

The ATPase domain of the membrane-anchored protease FtsH of E. coli has been crystallized and native data to 1.5 Å spacing have been collected using synchrotron radiation.