Structure of human translin at 2.2 Å resolution

The structure of human translin at 2.2 Å resolution is reported in space group C222₁. Translin forms a tetramer in the asymmetric unit. Although the monomer structure is almost the same as the crystal structure of murine translin in space group P2₁2₁2, the relative positions of the tetramers differ between the human and murine translins. This suggests that the multimerization of translin is flexible; the flexibility may be related to the binding to DNA/RNA.