(E)-1-(3-Methoxy-4-nitrophenyl)-2-(3,4,5-trimethoxyphenyl)ethene

The design and synthesis of new photoaffinity labeling (PAL) reagents is important in order to obtain detailed binding-site and structural information about tubulin. (E)-1-(3-Methoxy-4-nitrophenyl)-2-(3,4,5-trimethoxyphenyl)ethene, C₁₈H₁₉NO₆, crystallizes in the centrosymmetric space group P2₁/n (No. 14), with four molecules in the unit cell. The trans-stilbene base component is nearly planar (mean deviation 0.05 Å), with a dihedral angle between the two phenyl rings of 6.1°. Important bond distances include C=C 1.326 (3) Å and mean N-O 1.187 (8) Å.

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