organic compounds
In the title complex, C14H18N4O3.C12H14N4O2S.CH4O, the molecular association between trimethoprim {5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine; TMP} and sulfadimidine [4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide; SDMD] is maintained by two N-HN hydrogen bonds with no proton transfer from the sulfonamide imino N atom to the pyrimidine N atom of TMP. The methanol solvate molecule is linked to an O atom of the sulfonamido group through a strong O-HO interaction and does not seem to play an important role in the crystal-packing stabilization.
Supporting information
Crystallographic Information File (CIF) | |
Structure factor file (CIF format) |
CCDC reference: 128679