Substituted clonidine derivatives. III. 3,5-Dichloro-4-(imidazolidin-2-ylideneamino)benzyl alcohol and 3,5-dichloro-4-(1,3-diisobutyrylimidazolidin-2-ylideneamino)benzyl isobutyrate

In C₁₀H₁₁Cl₂N₃O (R₁ = H, R₂ = CH₂OH), (I), and C₂₂H₂₉Cl₂- N₃O₄ (R₁ = COCHMe₂, R₂ = CH₂OCOCHMe₂), (II), the bonds connecting the phenyl and imidazolidine rings are shorter than that observed in clonidine, indicating increased double-bond character. The imidazolidine rings adopt a half-chair conformation in both structures and the dihedral angles between the imidazolidine and phenyl rings are 86.97(7) and 66.32(6)° in (I), and 62.4(1)° in (II).

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