Download citation
Download citation
link to html
Mouse and Heligmosomoides polygyrus constitute a readily manipulated small-animal laboratory model for investigating host–nematode interactions. Two major forms of glutathione transferase (GST) are expressed in H. polygyrus adult worms following primary infection. One of these forms belongs to a new class of GST which has only been found in the nematode phylum and therefore presents a possible target for nematode control. In this study, crystals were obtained of a recombinant representative of this new GST class from H. polygyrus. These crystals belong to the triclinic space group P1, with unit-cell parameters a = 72.7, b = 74.0, c = 88.6 Å, α = 79.1, β = 80.1, γ = 81.5°, and are likely to contain four homodimers in the asymmetric unit. X-­ray diffraction data were collected to 1.8 Å resolution on station A1 at the Cornell High-Energy Synchrotron Source (CHESS).

Follow Acta Cryst. D
Sign up for e-alerts
Follow Acta Cryst. on Twitter
Follow us on facebook
Sign up for RSS feeds