A Clerodane Diterpene with Antibacterial Activity from Ajuga lupulina

The structure of a new diterpene, C₃₀H₄₆O₁₁, with anti­bacterial activity against Pseudomonas aeruginose and Escherichia coli, isolated from the fresh whole plants of Ajuga lupulina (Labiatae) was established to be 2β-hydroxy-2-methylbutanoyl-3α-lupulin (3-deoxy-14,15-dihydro-2-hydroxy-15-methoxycaryoptinol 2-methylbutanoate), by means of X-ray crystallographic analysis. The present study confirms that the two six-membered rings are in ideal chair conformations.

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