On the development of three new tools for organizing and sharing information in three-dimensional electron microscopy

Electron microscopy is a valuable tool for elucidating the three-dimensional structures of macromolecular complexes. As the field matures and the number of solved structures increases, the existence of infrastructures that keep this information organized and accessible is crucial. At the same time, standards and clearly described conventions facilitate software maintenance, benefit interoperability with other packages and allow data interchange. This work describes three developments promoting integrative biology, standard­ization and workflow processing, namely PeppeR, the EMX initiative and Scipion.