3α-Bikhaconine Acetone Solvate

The crystal structure of 3α-bikhaconine acetone solvate [1α,6α,16β-trimethoxy-4β-(methoxymethyl)aconitane-3α,8β,13β,14α-tetrol acetone solvate, C₂₅H₄₁NO₈.C₃H₆O], a C₁₉ norditerpenoid alkaloid, which has been partially synthesized from indaconitine, contains discrete molecules separated by normal van der Waals distances. The molecular dimensions are normal; the mean bond distances are C_sp3—N 1.471 (9), C_sp3—C_sp3 1.54 (2) and C_sp3—O 1.425 (14) Å. The fused-ring system contains two chair, one half-chair, two envelope and one boat conformation. There are both inter- and intramolecular hydrogen bonds, with O...O separations in the range 2.655 (3)–3.048 (3) Å and H...O interactions in the range 1.92–2.38 Å. There are no interactions between the alkaloid and the solvate molecules.

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