Mephentermine Hemisulfate Monohydrate: an Adrenergic Agent

The title molecule, a hydrated hemisulfate salt of ethyl(2-methyl-1-phenyl-2-propyl)ammonium, C₁₁H₁₈N⁺.0.5SO₄²⁻.H₂O, consists of a phenethylamine skeleton in which the N atom is protonated. There are two molecules in the asymmetric unit, with the S atom of the SO₄²⁻ ion lying on a pseudo-twofold axis. The ethylamine side chain is in an extended conformation in both the symmetry-independent molecules. The distance of the N atom from the centre of the benzene ring is 5.1 Å for molecule 1 and 5.3 Å for molecule 2. The packing is stabilized by N—H...O and O—H...O hydrogen bonds.

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