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In the title complex, C14H18N4O3.C12H14N4O2S.CH4O, the molecular association between trimethoprim {5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine; TMP} and sulfadimidine [4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide; SDMD] is maintained by two N-H...N hydrogen bonds with no proton transfer from the sulfonamide imino N atom to the pyrimidine N atom of TMP. The methanol solvate molecule is linked to an O atom of the sulfonamido group through a strong O-H...O interaction and does not seem to play an important role in the crystal-packing stabilization.

Supporting information

cif

Crystallographic Information File (CIF)
Contains datablocks global, sk1047

hkl

Structure factor file (CIF format)
Supplementary material

CCDC reference: 128679

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