A Cytosine and Tryptophan Hybrid Dipeptide: Cytosinyl-L-tryptophan-Water (2/6)

The hybrid dipeptide of the title compound, 2(C₁₈H₁₉N₅O₄).6H₂O, containing cytosine base and L-tryptophan was crystallized in hexahydrated form; the solvent occupies 12% by weight of the asymmetric unit. Two independent molecules were distinguished by the different direction of their indole rings. All polar atoms of the title compound participate in H-bond formation, and the tight network is built by combination with solvent-mediated H-bonds. A [pi]-[pi] electron interaction was observed between the indole and nucleic base; it is facilitated by hydrogen bonds.

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