Buy article online - an online subscription or single-article purchase is required to access this article.
computer programs
An algorithm to determine the exact profiles of digitized spots having arbitrary shapes and sizes is described. It does not require any prior knowledge of crystallographic parameters and can be applied to the digitized data set of any random distribution of arbitrarily shaped peaks of finite size having an average intensity significantly higher than a nearly constant background. Application to the case of oscillation photography data from protein crystals is described.