organic compounds\(\def\hfill{\hskip 5em}\def\hfil{\hskip 3em}\def\eqno#1{\hfil {#1}}\)

Journal logoCRYSTALLOGRAPHIC
COMMUNICATIONS
ISSN: 2056-9890

(E)-Methyl N′-(3-meth­oxy­benzyl­­idene)hydrazine­carboxyl­ate

aDepartment of Chemical Engineering, Hangzhou Vocational and Technical College, Hangzhou 310018, People's Republic of China, bThe Children's Hospital of Zhejiang University, School of Medicine, Hangzhou 310003, People's Republic of China, and cResearch Center of Analysis and Measurement, Zhejiang University of Technology, Hangzhou 310014, People's Republic of China
*Correspondence e-mail: zgdhxc@126.com

(Received 18 August 2009; accepted 20 August 2009; online 26 August 2009)

The title compound, C10H12N2O3, crystallizes with two independent mol­ecules in the asymmetric unit which differ in the orientation of the meth­oxy group. Each independent mol­ecule adopts a trans configuration with respect to the C=N bond. In the crystal structure, mol­ecules are linked into chains running along [001] by N—H⋯O and N—H⋯N hydrogen bonds. In addition, an inter­molecular C—H⋯π inter­action is observed.

Related literature

For general background to the properties of benzaldehyde­hydrazone derivatives, see: Parashar et al. (1988[Parashar, R. K., Sharma, R. C., Kumar, A. & Mohanm, G. (1988). Inorg. Chim. Acta, 151, 201-208.]); Hadjoudis et al. (1987[Hadjoudis, E., Vittorakis, M. & Moustakali-Mavridis, J. (1987). Tetrahedron, 43, 1345-1360.]); Borg et al. (1999[Borg, S., Vollinga, R. C., Labarre, M., Payza, K., Terenius, L. & Luthman, K. (1999). J. Med. Chem. 42, 4331-4342.]); Kahwa et al. (1986[Kahwa, I. A., Selbin, J., Hsieh, T. Y. & Laine, R. A. (1986). Inorg. Chim. Acta, 151, 201-208.]); Santos et al. (2001[Santos, M. L. P., Bagatin, I. A., Pereira, E. M. & Ferreira, A. M. D. C. (2001). J. Chem. Soc. Dalton Trans. pp. 838-844.]). For a related structure, see: Shang et al. (2007[Shang, Z.-H., Zhang, H.-L. & Ding, Y. (2007). Acta Cryst. E63, o3394.]).

[Scheme 1]

Experimental

Crystal data
  • C10H12N2O3

  • Mr = 208.22

  • Monoclinic, P 21 /c

  • a = 18.207 (3) Å

  • b = 7.3677 (12) Å

  • c = 16.552 (3) Å

  • β = 104.243 (5)°

  • V = 2152.1 (6) Å3

  • Z = 8

  • Mo Kα radiation

  • μ = 0.10 mm−1

  • T = 223 K

  • 0.24 × 0.21 × 0.19 mm

Data collection
  • Bruker SMART CCD area-detector diffractometer

  • Absorption correction: multi-scan (SADABS; Bruker, 2002[Bruker (2002). SMART, SAINT and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA.]) Tmin = 0.977, Tmax = 0.989

  • 11364 measured reflections

  • 3790 independent reflections

  • 3033 reflections with I > 2σ(I)

  • Rint = 0.020

Refinement
  • R[F2 > 2σ(F2)] = 0.037

  • wR(F2) = 0.109

  • S = 1.07

  • 3790 reflections

  • 276 parameters

  • H-atom parameters constrained

  • Δρmax = 0.20 e Å−3

  • Δρmin = −0.17 e Å−3

Table 1
Hydrogen-bond geometry (Å, °)

D—H⋯A D—H H⋯A DA D—H⋯A
N2—H2⋯O5 0.86 2.07 2.9188 (18) 172
N4—H4⋯O2i 0.86 2.25 2.8365 (17) 126
N4—H4⋯N1i 0.86 2.55 3.3883 (19) 164
C11—H11BCg1ii 0.96 2.91 3.776 (3) 150
Symmetry codes: (i) [x, -y+{\script{3\over 2}}, z+{\script{1\over 2}}]; (ii) -x+1, -y+1, -z+1. Cg1 is the centroid of the C12–C17 ring.

Data collection: SMART (Bruker, 2002[Bruker (2002). SMART, SAINT and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA.]); cell refinement: SAINT (Bruker, 2002[Bruker (2002). SMART, SAINT and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA.]); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008[Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.]); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008[Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.]); molecular graphics: SHELXTL (Sheldrick, 2008[Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.]); software used to prepare material for publication: SHELXTL.

Supporting information


Comment top

Benzaldehydehydrazone derivatives have attracted much attention due to their pharmacological activity (Parashar et al., 1988) and their photochromic properties (Hadjoudis et al., 1987). They are important intermediates of 1,3,4-oxadiazoles, which have been reported to be versatile compounds with many interesting properties (Borg et al., 1999). Metal complexes based on Schiff bases have received considerable attention because they can be utilized as model compounds of active centres in various proteins and enzymes (Kahwa et al., 1986; Santos et al., 2001). We report here the crystal structure of the title compound (Fig. 1).

The title compound contains two independent, but almost identical molecules in the asymmetric unit. Each independent molecule adopts a trans configuration with respect to the CN bond. The N1/N2/O2/O3/C8/C9/C10 and N3/N4/O5/O6/C18/C19/C20 planes form dihedral angles of 4.51 (6)° and 13.80 (6)°, respectively, with the C2—C7 and C12—C17 planes. The dihedral angle between the two independent benzene rings is 59.18 (6)°. Bond lengths and angles are comparable to those observed for methylN'-[(E)-4-methoxybenzylidene]hydrazinecarboxylate (Shang et al., 2007).

In the crystal structure, molecules are linked into chains running along the [001] by N—H···O and N—H···N hydrogen bonds. In addition, an intermolecular C—H···π interaction is observed (Table 1).

Related literature top

For general background to the properties of benzaldehydehydrazone derivatives, see: Parashar et al. (1988); Hadjoudis et al. (1987); Borg et al. (1999); Kahwa et al. (1986); Santos et al. (2001). For a related structure, see: Shang et al. (2007). Cg1 is the centroid of the C12–C17 ring.

Experimental top

3-Methoxybenzaldehyde (1.36 g, 0.01 mol) and methyl hydrazinecarboxylate (0.90 g, 0.01 mol) were dissolved in stirred methanol (20 ml) and left for 2.5 h at room temperature. The resulting solid was filtered off and recrystallized from ethanol to give the title compound in 95% yield. Single crystals suitable for X-ray analysis were obtained by slow evaporation of an ethanol solution at room temperature (m.p. 436–438 K).

Refinement top

H atoms were positioned geometrically (N-H = 0.86 Å and C-H = 0.93 or 0.96 Å) and refined using a riding model, with Uiso(H) = 1.2Ueq(C,N) and 1.5Ueq(Cmethyl). A rotating group model was used for the methyl groups.

Computing details top

Data collection: SMART (Bruker, 2002); cell refinement: SAINT (Bruker, 2002); data reduction: SAINT (Bruker, 2002); program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: SHELXTL (Sheldrick, 2008); software used to prepare material for publication: SHELXTL (Sheldrick, 2008).

Figures top
[Figure 1] Fig. 1. The asymmetric unit of the title compound. Displacement ellipsoids are drawn at the 40% probability level. The dashed line indicates a hydrogen bond.
[Figure 2] Fig. 2. Crystal packing of the title compound. Hydrogen bonds are shown as dashed lines.
(E)-Methyl N'-(3-methoxybenzylidene)hydrazinecarboxylate top
Crystal data top
C10H12N2O3F(000) = 880
Mr = 208.22Dx = 1.285 Mg m3
Monoclinic, P21/cMo Kα radiation, λ = 0.71073 Å
Hall symbol: -P 2ybcCell parameters from 3790 reflections
a = 18.207 (3) Åθ = 2.3–25.0°
b = 7.3677 (12) ŵ = 0.10 mm1
c = 16.552 (3) ÅT = 223 K
β = 104.243 (5)°Block, colourless
V = 2152.1 (6) Å30.24 × 0.21 × 0.19 mm
Z = 8
Data collection top
Bruker SMART CCD area-detector
diffractometer
3790 independent reflections
Radiation source: fine-focus sealed tube3033 reflections with I > 2σ(I)
Graphite monochromatorRint = 0.020
ϕ and ω scansθmax = 25.0°, θmin = 2.3°
Absorption correction: multi-scan
(SADABS; Bruker, 2002)
h = 2118
Tmin = 0.977, Tmax = 0.989k = 88
11364 measured reflectionsl = 1919
Refinement top
Refinement on F2Secondary atom site location: difference Fourier map
Least-squares matrix: fullHydrogen site location: inferred from neighbouring sites
R[F2 > 2σ(F2)] = 0.037H-atom parameters constrained
wR(F2) = 0.109 w = 1/[σ2(Fo2) + (0.054P)2 + 0.3311P]
where P = (Fo2 + 2Fc2)/3
S = 1.07(Δ/σ)max = 0.004
3790 reflectionsΔρmax = 0.20 e Å3
276 parametersΔρmin = 0.17 e Å3
0 restraintsExtinction correction: SHELXL97 (Sheldrick, 2008), Fc*=kFc[1+0.001xFc2λ3/sin(2θ)]-1/4
Primary atom site location: structure-invariant direct methodsExtinction coefficient: 0.0115 (12)
Crystal data top
C10H12N2O3V = 2152.1 (6) Å3
Mr = 208.22Z = 8
Monoclinic, P21/cMo Kα radiation
a = 18.207 (3) ŵ = 0.10 mm1
b = 7.3677 (12) ÅT = 223 K
c = 16.552 (3) Å0.24 × 0.21 × 0.19 mm
β = 104.243 (5)°
Data collection top
Bruker SMART CCD area-detector
diffractometer
3790 independent reflections
Absorption correction: multi-scan
(SADABS; Bruker, 2002)
3033 reflections with I > 2σ(I)
Tmin = 0.977, Tmax = 0.989Rint = 0.020
11364 measured reflections
Refinement top
R[F2 > 2σ(F2)] = 0.0370 restraints
wR(F2) = 0.109H-atom parameters constrained
S = 1.07Δρmax = 0.20 e Å3
3790 reflectionsΔρmin = 0.17 e Å3
276 parameters
Special details top

Geometry. All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes.

Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > 2sigma(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger.

Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å2) top
xyzUiso*/Ueq
O10.68188 (7)1.33813 (15)0.17091 (7)0.0626 (3)
O20.86739 (7)0.49630 (16)0.12622 (7)0.0661 (3)
O30.92117 (7)0.34574 (16)0.00794 (8)0.0717 (4)
O40.55036 (7)0.73143 (19)0.03581 (8)0.0788 (4)
O50.90715 (7)0.5763 (2)0.18325 (7)0.0792 (4)
O60.96333 (6)0.64573 (18)0.31586 (7)0.0690 (4)
N10.82614 (7)0.75999 (16)0.02931 (7)0.0491 (3)
N20.86458 (7)0.60387 (17)0.00177 (8)0.0545 (3)
H20.87690.58360.05460.065*
N30.77335 (7)0.69523 (16)0.21361 (7)0.0492 (3)
N40.84157 (7)0.68885 (19)0.27209 (8)0.0574 (4)
H40.84420.72100.32270.069*
C10.69744 (12)1.2445 (3)0.23962 (10)0.0724 (5)
H1A0.67821.31320.28960.109*
H1B0.67351.12760.24490.109*
H1C0.75121.22940.23090.109*
C20.70930 (8)1.2656 (2)0.09344 (9)0.0482 (4)
C30.70053 (9)1.3743 (2)0.02757 (10)0.0559 (4)
H30.67741.48730.03820.067*
C40.74387 (8)1.0972 (2)0.07774 (9)0.0478 (4)
H4A0.75001.02490.12170.057*
C50.72602 (10)1.3148 (2)0.05299 (10)0.0612 (4)
H50.72041.38790.09690.073*
C60.76013 (9)1.1460 (2)0.06930 (10)0.0567 (4)
H60.77681.10580.12400.068*
C70.76944 (8)1.0368 (2)0.00429 (9)0.0475 (4)
C80.80804 (9)0.8620 (2)0.02498 (9)0.0510 (4)
H80.81990.82390.08020.061*
C90.88263 (9)0.4835 (2)0.05143 (10)0.0522 (4)
C100.94571 (13)0.2072 (3)0.05631 (15)0.0888 (6)
H10A0.98140.12910.02010.133*
H10B0.96940.26250.09600.133*
H10C0.90280.13730.08530.133*
C110.47641 (11)0.7249 (3)0.09038 (13)0.0860 (6)
H11A0.48040.70210.14630.129*
H11B0.45130.83880.08850.129*
H11C0.44780.62930.07310.129*
C120.55619 (9)0.7559 (2)0.04734 (10)0.0567 (4)
C130.49554 (11)0.7833 (3)0.08170 (14)0.0777 (6)
H130.44640.78620.04800.093*
C140.62919 (9)0.7513 (2)0.09829 (10)0.0518 (4)
H140.67000.73370.07470.062*
C150.50852 (12)0.8064 (4)0.16661 (15)0.0962 (7)
H150.46760.82530.18990.115*
C160.58066 (11)0.8024 (3)0.21795 (13)0.0812 (6)
H160.58820.81940.27510.097*
C170.64204 (9)0.7725 (2)0.18355 (10)0.0531 (4)
C180.71842 (9)0.7617 (2)0.23885 (10)0.0528 (4)
H180.72690.80410.29330.063*
C190.90395 (9)0.6325 (2)0.25016 (9)0.0504 (4)
C201.03667 (10)0.6043 (3)0.30340 (14)0.0839 (6)
H20A1.07500.66100.34630.126*
H20B1.04010.64890.25000.126*
H20C1.04410.47520.30560.126*
Atomic displacement parameters (Å2) top
U11U22U33U12U13U23
O10.0750 (8)0.0619 (7)0.0499 (6)0.0148 (6)0.0135 (5)0.0052 (5)
O20.0832 (8)0.0608 (7)0.0546 (7)0.0141 (6)0.0177 (6)0.0080 (5)
O30.0808 (9)0.0605 (7)0.0716 (8)0.0215 (6)0.0150 (6)0.0188 (6)
O40.0582 (8)0.1052 (10)0.0640 (8)0.0062 (7)0.0020 (6)0.0096 (7)
O50.0762 (9)0.1133 (11)0.0448 (7)0.0302 (8)0.0089 (6)0.0079 (7)
O60.0538 (7)0.0895 (9)0.0555 (7)0.0082 (6)0.0021 (5)0.0090 (6)
N10.0505 (8)0.0482 (7)0.0468 (7)0.0021 (6)0.0085 (6)0.0069 (5)
N20.0622 (8)0.0538 (7)0.0444 (7)0.0074 (6)0.0071 (6)0.0094 (6)
N30.0509 (8)0.0497 (7)0.0434 (7)0.0003 (6)0.0045 (6)0.0027 (5)
N40.0532 (8)0.0758 (9)0.0387 (7)0.0044 (7)0.0026 (6)0.0129 (6)
C10.0914 (14)0.0770 (12)0.0465 (9)0.0169 (10)0.0127 (9)0.0039 (8)
C20.0458 (9)0.0518 (8)0.0477 (8)0.0018 (7)0.0126 (6)0.0009 (6)
C30.0568 (10)0.0507 (8)0.0629 (10)0.0035 (7)0.0201 (8)0.0039 (7)
C40.0493 (9)0.0511 (8)0.0437 (8)0.0004 (7)0.0129 (6)0.0042 (6)
C50.0685 (11)0.0645 (10)0.0544 (10)0.0014 (9)0.0226 (8)0.0122 (8)
C60.0589 (10)0.0689 (10)0.0438 (8)0.0003 (8)0.0157 (7)0.0013 (7)
C70.0432 (8)0.0536 (8)0.0468 (8)0.0038 (7)0.0132 (6)0.0006 (6)
C80.0519 (9)0.0573 (9)0.0431 (8)0.0014 (7)0.0104 (7)0.0057 (7)
C90.0507 (9)0.0493 (8)0.0546 (9)0.0015 (7)0.0091 (7)0.0112 (7)
C100.0927 (15)0.0646 (11)0.1145 (17)0.0286 (11)0.0360 (13)0.0127 (11)
C110.0681 (13)0.0987 (15)0.0760 (13)0.0005 (11)0.0113 (10)0.0085 (11)
C120.0513 (10)0.0520 (9)0.0634 (11)0.0023 (7)0.0077 (8)0.0035 (7)
C130.0454 (10)0.0951 (14)0.0882 (15)0.0051 (10)0.0079 (9)0.0067 (11)
C140.0457 (9)0.0492 (8)0.0596 (9)0.0009 (7)0.0112 (7)0.0031 (7)
C150.0515 (12)0.152 (2)0.0911 (16)0.0039 (13)0.0284 (11)0.0137 (15)
C160.0600 (12)0.1185 (17)0.0685 (12)0.0066 (11)0.0224 (10)0.0107 (11)
C170.0496 (9)0.0503 (8)0.0601 (10)0.0052 (7)0.0149 (7)0.0030 (7)
C180.0571 (10)0.0539 (9)0.0467 (8)0.0048 (7)0.0116 (7)0.0053 (7)
C190.0565 (10)0.0491 (8)0.0414 (8)0.0052 (7)0.0044 (7)0.0021 (6)
C200.0541 (12)0.0970 (15)0.0941 (15)0.0160 (10)0.0058 (10)0.0073 (12)
Geometric parameters (Å, º) top
O1—C21.3654 (18)C5—C61.387 (2)
O1—C11.417 (2)C5—H50.93
O2—C91.2039 (18)C6—C71.387 (2)
O3—C91.3387 (18)C6—H60.93
O3—C101.435 (2)C7—C81.467 (2)
O4—C121.366 (2)C8—H80.93
O4—C111.426 (2)C10—H10A0.96
O5—C191.1971 (18)C10—H10B0.96
O6—C191.3351 (18)C10—H10C0.96
O6—C201.433 (2)C11—H11A0.96
N1—C81.2757 (19)C11—H11B0.96
N1—N21.3785 (17)C11—H11C0.96
N2—C91.346 (2)C12—C131.376 (3)
N2—H20.86C12—C141.388 (2)
N3—C181.273 (2)C13—C151.377 (3)
N3—N41.3749 (17)C13—H130.93
N4—C191.341 (2)C14—C171.381 (2)
N4—H40.86C14—H140.93
C1—H1A0.96C15—C161.378 (3)
C1—H1B0.96C15—H150.93
C1—H1C0.96C16—C171.391 (2)
C2—C41.386 (2)C16—H160.93
C2—C31.393 (2)C17—C181.467 (2)
C3—C51.372 (2)C18—H180.93
C3—H30.93C20—H20A0.96
C4—C71.396 (2)C20—H20B0.96
C4—H4A0.93C20—H20C0.96
C2—O1—C1117.64 (12)O3—C10—H10A109.5
C9—O3—C10115.68 (14)O3—C10—H10B109.5
C12—O4—C11118.03 (15)H10A—C10—H10B109.5
C19—O6—C20117.62 (14)O3—C10—H10C109.5
C8—N1—N2115.11 (12)H10A—C10—H10C109.5
C9—N2—N1119.26 (12)H10B—C10—H10C109.5
C9—N2—H2120.4O4—C11—H11A109.5
N1—N2—H2120.4O4—C11—H11B109.5
C18—N3—N4115.39 (13)H11A—C11—H11B109.5
C19—N4—N3119.91 (12)O4—C11—H11C109.5
C19—N4—H4120.0H11A—C11—H11C109.5
N3—N4—H4120.0H11B—C11—H11C109.5
O1—C1—H1A109.5O4—C12—C13124.38 (16)
O1—C1—H1B109.5O4—C12—C14115.73 (15)
H1A—C1—H1B109.5C13—C12—C14119.90 (16)
O1—C1—H1C109.5C12—C13—C15119.10 (17)
H1A—C1—H1C109.5C12—C13—H13120.4
H1B—C1—H1C109.5C15—C13—H13120.4
O1—C2—C4124.80 (13)C17—C14—C12120.93 (16)
O1—C2—C3115.07 (13)C17—C14—H14119.5
C4—C2—C3120.13 (14)C12—C14—H14119.5
C5—C3—C2120.02 (15)C13—C15—C16121.65 (19)
C5—C3—H3120.0C13—C15—H15119.2
C2—C3—H3120.0C16—C15—H15119.2
C2—C4—C7119.68 (14)C15—C16—C17119.41 (19)
C2—C4—H4A120.2C15—C16—H16120.3
C7—C4—H4A120.2C17—C16—H16120.3
C3—C5—C6120.27 (15)C14—C17—C16119.00 (16)
C3—C5—H5119.9C14—C17—C18121.84 (15)
C6—C5—H5119.9C16—C17—C18119.15 (16)
C7—C6—C5120.23 (15)N3—C18—C17121.13 (14)
C7—C6—H6119.9N3—C18—H18119.4
C5—C6—H6119.9C17—C18—H18119.4
C6—C7—C4119.66 (14)O5—C19—O6124.39 (15)
C6—C7—C8118.10 (13)O5—C19—N4126.52 (14)
C4—C7—C8122.22 (14)O6—C19—N4109.08 (13)
N1—C8—C7123.03 (13)O6—C20—H20A109.5
N1—C8—H8118.5O6—C20—H20B109.5
C7—C8—H8118.5H20A—C20—H20B109.5
O2—C9—O3124.75 (15)O6—C20—H20C109.5
O2—C9—N2126.11 (14)H20A—C20—H20C109.5
O3—C9—N2109.14 (13)H20B—C20—H20C109.5
C8—N1—N2—C9176.68 (14)N1—N2—C9—O3178.40 (12)
C18—N3—N4—C19175.58 (14)C11—O4—C12—C133.2 (3)
C1—O1—C2—C47.6 (2)C11—O4—C12—C14176.59 (15)
C1—O1—C2—C3172.35 (15)O4—C12—C13—C15180.0 (2)
O1—C2—C3—C5179.99 (15)C14—C12—C13—C150.2 (3)
C4—C2—C3—C50.1 (2)O4—C12—C14—C17179.29 (14)
O1—C2—C4—C7179.72 (14)C13—C12—C14—C170.5 (2)
C3—C2—C4—C70.4 (2)C12—C13—C15—C160.2 (4)
C2—C3—C5—C60.4 (3)C13—C15—C16—C170.6 (4)
C3—C5—C6—C70.7 (3)C12—C14—C17—C161.3 (2)
C5—C6—C7—C40.4 (2)C12—C14—C17—C18177.79 (14)
C5—C6—C7—C8178.06 (15)C15—C16—C17—C141.3 (3)
C2—C4—C7—C60.1 (2)C15—C16—C17—C18177.8 (2)
C2—C4—C7—C8178.51 (13)N4—N3—C18—C17178.49 (13)
N2—N1—C8—C7177.72 (13)C14—C17—C18—N315.0 (2)
C6—C7—C8—N1172.84 (15)C16—C17—C18—N3164.04 (17)
C4—C7—C8—N15.6 (2)C20—O6—C19—O55.5 (2)
C10—O3—C9—O20.7 (2)C20—O6—C19—N4175.48 (15)
C10—O3—C9—N2178.90 (15)N3—N4—C19—O53.8 (3)
N1—N2—C9—O21.2 (2)N3—N4—C19—O6177.20 (13)
Hydrogen-bond geometry (Å, º) top
D—H···AD—HH···AD···AD—H···A
N2—H2···O50.862.072.9188 (18)172
N4—H4···O2i0.862.252.8365 (17)126
N4—H4···N1i0.862.553.3883 (19)164
C11—H11B···Cg1ii0.962.913.776 (3)150
Symmetry codes: (i) x, y+3/2, z+1/2; (ii) x+1, y+1, z+1.

Experimental details

Crystal data
Chemical formulaC10H12N2O3
Mr208.22
Crystal system, space groupMonoclinic, P21/c
Temperature (K)223
a, b, c (Å)18.207 (3), 7.3677 (12), 16.552 (3)
β (°) 104.243 (5)
V3)2152.1 (6)
Z8
Radiation typeMo Kα
µ (mm1)0.10
Crystal size (mm)0.24 × 0.21 × 0.19
Data collection
DiffractometerBruker SMART CCD area-detector
diffractometer
Absorption correctionMulti-scan
(SADABS; Bruker, 2002)
Tmin, Tmax0.977, 0.989
No. of measured, independent and
observed [I > 2σ(I)] reflections
11364, 3790, 3033
Rint0.020
(sin θ/λ)max1)0.596
Refinement
R[F2 > 2σ(F2)], wR(F2), S 0.037, 0.109, 1.07
No. of reflections3790
No. of parameters276
H-atom treatmentH-atom parameters constrained
Δρmax, Δρmin (e Å3)0.20, 0.17

Computer programs: SMART (Bruker, 2002), SAINT (Bruker, 2002), SHELXS97 (Sheldrick, 2008), SHELXL97 (Sheldrick, 2008), SHELXTL (Sheldrick, 2008).

Hydrogen-bond geometry (Å, º) top
D—H···AD—HH···AD···AD—H···A
N2—H2···O50.862.072.9188 (18)172
N4—H4···O2i0.862.252.8365 (17)126
N4—H4···N1i0.862.553.3883 (19)164
C11—H11B···Cg1ii0.962.913.776 (3)150
Symmetry codes: (i) x, y+3/2, z+1/2; (ii) x+1, y+1, z+1.
 

Acknowledgements

The authors thank the Science and Technology Project of Zhejiang Province (grant No. 2007 F70077) and Hangzhou Vocational and Technical College for financial support.

References

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First citationSantos, M. L. P., Bagatin, I. A., Pereira, E. M. & Ferreira, A. M. D. C. (2001). J. Chem. Soc. Dalton Trans. pp. 838–844.  Web of Science CrossRef Google Scholar
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