A cis,trans,cis,cis-[4.5.5.5]Fenestrane Derivative

The title compound, rel-(1R,4R,7S,10R)-7-(tert-butyldimethylsilyloxy)tetracyclo [5.4.1.0^4,12.0^10,12]dodecan-2-one, C₁₈H₃₀O₂Si, has been prepared and its structure determined. The geometry of the central C(C)₄ substructure of the fenestrane skeleton shows a considerable distortion from an ideal tetrahedral arrangement towards planarity. Values of 127.0 (2) and 131.1 (2)° are observed for the bond angles at the bridgehead atoms of the trans-bicyclo[3.3.0]octane subunit.

-1