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The two pyrrolidine rings in the title compound, C
25H
22N
2O
6, adopt envelope conformations. Molecules are stabilized by intramolecular O—H
O hydrogen bonds, and linked into centrosymmetric dimers by intermolecular N—H
O hydrogen bonds.
Supporting information
CCDC reference: 640262
Key indicators
- Single-crystal X-ray study
- T = 273 K
- Mean (C-C) = 0.003 Å
- R factor = 0.063
- wR factor = 0.182
- Data-to-parameter ratio = 16.2
checkCIF/PLATON results
No syntax errors found
Alert level C
DIFMX01_ALERT_2_C The maximum difference density is > 0.1*ZMAX*0.75
_refine_diff_density_max given = 0.688
Test value = 0.600
DIFMX02_ALERT_1_C The maximum difference density is > 0.1*ZMAX*0.75
The relevant atom site should be identified.
PLAT094_ALERT_2_C Ratio of Maximum / Minimum Residual Density .... 2.77
PLAT097_ALERT_2_C Maximum (Positive) Residual Density ............ 0.69 e/A
PLAT154_ALERT_1_C The su's on the Cell Angles are Equal (x 10000) 100 Deg.
PLAT180_ALERT_3_C Check Cell Rounding: # of Values Ending with 0 = 3
PLAT320_ALERT_2_C Check Hybridisation of C4 in Main Residue . ?
0 ALERT level A = In general: serious problem
0 ALERT level B = Potentially serious problem
7 ALERT level C = Check and explain
0 ALERT level G = General alerts; check
2 ALERT type 1 CIF construction/syntax error, inconsistent or missing data
4 ALERT type 2 Indicator that the structure model may be wrong or deficient
1 ALERT type 3 Indicator that the structure quality may be low
0 ALERT type 4 Improvement, methodology, query or suggestion
0 ALERT type 5 Informative message, check
Data collection: SMART (Bruker, 2001); cell refinement: SAINT (Bruker, 2001); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 1997); program(s) used to refine structure: SHELXL97 (Sheldrick, 1997); molecular graphics: PLATON (Spek, 2003); software used to prepare material for publication: SHELXL97 and PARST (Nardelli, 1995).
Methyl
1'-(2-hydroxy-1,3-dioxo-2,3-dihydro-1
H-indan-2-yl)-2-oxo-5',6',7',7a'-
tetrahydrospiro[1
H-indole-3,3'(2
H,2'
H)-1'
H-pyrrolizine]-1'-carboxylate
top
Crystal data top
C25H22N2O6 | Z = 2 |
Mr = 446.45 | F(000) = 468 |
Triclinic, P1 | Dx = 1.397 Mg m−3 |
Hall symbol: -P 1 | Mo Kα radiation, λ = 0.71073 Å |
a = 8.6659 (6) Å | Cell parameters from 2513 reflections |
b = 8.6988 (6) Å | θ = 2.4–25.0° |
c = 14.5841 (11) Å | µ = 0.10 mm−1 |
α = 84.389 (1)° | T = 273 K |
β = 85.373 (1)° | Block, pale yellow |
γ = 76.402 (1)° | 0.25 × 0.22 × 0.21 mm |
V = 1061.56 (13) Å3 | |
Data collection top
Bruker SMART APEX CCD diffractometer | 3879 reflections with I > 2σ(I) |
Radiation source: fine-focus sealed tube | Rint = 0.018 |
Graphite monochromator | θmax = 28.0°, θmin = 2.4° |
ω scans | h = −11→11 |
12205 measured reflections | k = −11→11 |
4842 independent reflections | l = −18→18 |
Refinement top
Refinement on F2 | Primary atom site location: structure-invariant direct methods |
Least-squares matrix: full | Secondary atom site location: difference Fourier map |
R[F2 > 2σ(F2)] = 0.063 | Hydrogen site location: inferred from neighbouring sites |
wR(F2) = 0.182 | H-atom parameters constrained |
S = 1.01 | w = 1/[σ2(Fo2) + (0.1125P)2 + 0.286P] where P = (Fo2 + 2Fc2)/3 |
4842 reflections | (Δ/σ)max = 0.010 |
299 parameters | Δρmax = 0.69 e Å−3 |
0 restraints | Δρmin = −0.25 e Å−3 |
Special details top
Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes)
are estimated using the full covariance matrix. The cell e.s.d.'s are taken
into account individually in the estimation of e.s.d.'s in distances, angles
and torsion angles; correlations between e.s.d.'s in cell parameters are only
used when they are defined by crystal symmetry. An approximate (isotropic)
treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s.
planes. |
Refinement. Refinement of F2 against ALL reflections. The weighted R-factor
wR and goodness of fit S are based on F2, conventional
R-factors R are based on F, with F set to zero for
negative F2. The threshold expression of F2 >
σ(F2) is used only for calculating R-factors(gt) etc.
and is not relevant to the choice of reflections for refinement.
R-factors based on F2 are statistically about twice as large
as those based on F, and R- factors based on ALL data will be
even larger. |
Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å2) top | x | y | z | Uiso*/Ueq | |
C1 | 1.3110 (3) | 0.6693 (4) | 0.26726 (17) | 0.0672 (7) | |
H1A | 1.3705 | 0.7466 | 0.2417 | 0.081* | |
H1B | 1.3701 | 0.5642 | 0.2531 | 0.081* | |
C2 | 1.2764 (3) | 0.6784 (4) | 0.37141 (16) | 0.0682 (7) | |
H2A | 1.3302 | 0.7522 | 0.3937 | 0.082* | |
H2B | 1.3134 | 0.5749 | 0.4037 | 0.082* | |
C3 | 1.0952 (3) | 0.7354 (3) | 0.38813 (14) | 0.0521 (5) | |
H3A | 1.0458 | 0.6475 | 0.4075 | 0.063* | |
H3B | 1.0683 | 0.8127 | 0.4339 | 0.063* | |
C4 | 1.0469 (2) | 0.8104 (2) | 0.29255 (12) | 0.0400 (4) | |
H4 | 1.0719 | 0.9152 | 0.2836 | 0.048* | |
C5 | 0.8825 (2) | 0.8220 (2) | 0.25218 (12) | 0.0351 (4) | |
C6 | 0.9293 (2) | 0.7737 (2) | 0.15133 (12) | 0.0383 (4) | |
H6A | 0.8903 | 0.6812 | 0.1415 | 0.046* | |
H6B | 0.8832 | 0.8599 | 0.1073 | 0.046* | |
C7 | 1.1132 (2) | 0.7363 (2) | 0.13871 (12) | 0.0377 (4) | |
C8 | 0.7933 (2) | 0.7079 (2) | 0.30598 (12) | 0.0384 (4) | |
C9 | 0.7767 (4) | 0.4424 (3) | 0.3396 (2) | 0.0753 (8) | |
H9A | 0.8031 | 0.4241 | 0.4030 | 0.113* | |
H9B | 0.8096 | 0.3447 | 0.3104 | 0.113* | |
H9C | 0.6639 | 0.4814 | 0.3365 | 0.113* | |
C10 | 0.7745 (2) | 0.9919 (2) | 0.25456 (12) | 0.0367 (4) | |
C11 | 0.7262 (2) | 1.0500 (2) | 0.35236 (13) | 0.0404 (4) | |
C12 | 0.5512 (2) | 1.1085 (2) | 0.36014 (13) | 0.0410 (4) | |
C13 | 0.4550 (3) | 1.1773 (3) | 0.43261 (15) | 0.0571 (6) | |
H13 | 0.4982 | 1.1957 | 0.4857 | 0.069* | |
C14 | 0.2929 (3) | 1.2178 (4) | 0.42341 (19) | 0.0759 (8) | |
H14 | 0.2259 | 1.2636 | 0.4714 | 0.091* | |
C15 | 0.2274 (3) | 1.1916 (4) | 0.3441 (2) | 0.0800 (9) | |
H15 | 0.1177 | 1.2197 | 0.3400 | 0.096* | |
C16 | 0.3226 (3) | 1.1248 (3) | 0.27145 (17) | 0.0596 (6) | |
H16 | 0.2790 | 1.1078 | 0.2181 | 0.071* | |
C17 | 0.4855 (2) | 1.0837 (2) | 0.28042 (13) | 0.0419 (4) | |
C18 | 0.6108 (2) | 1.0087 (2) | 0.21415 (12) | 0.0390 (4) | |
C19 | 1.1659 (2) | 0.8799 (2) | 0.08540 (13) | 0.0403 (4) | |
C20 | 1.2695 (2) | 0.6656 (2) | 0.00240 (12) | 0.0398 (4) | |
C21 | 1.3469 (2) | 0.5729 (3) | −0.06636 (14) | 0.0481 (5) | |
H21 | 1.3988 | 0.6158 | −0.1173 | 0.058* | |
C22 | 1.3443 (3) | 0.4142 (3) | −0.05656 (15) | 0.0524 (5) | |
H22 | 1.3965 | 0.3485 | −0.1015 | 0.063* | |
C23 | 1.2657 (3) | 0.3508 (3) | 0.01876 (16) | 0.0536 (5) | |
H23 | 1.2668 | 0.2431 | 0.0243 | 0.064* | |
C24 | 1.1849 (3) | 0.4469 (2) | 0.08638 (15) | 0.0502 (5) | |
H24 | 1.1298 | 0.4051 | 0.1364 | 0.060* | |
C25 | 1.1880 (2) | 0.6050 (2) | 0.07774 (12) | 0.0398 (4) | |
N1 | 1.1568 (2) | 0.7043 (2) | 0.23330 (11) | 0.0489 (4) | |
N2 | 1.2578 (2) | 0.8283 (2) | 0.01102 (11) | 0.0452 (4) | |
H2 | 1.3042 | 0.8875 | −0.0270 | 0.054* | |
O1 | 0.8571 (2) | 0.55744 (17) | 0.29303 (12) | 0.0620 (5) | |
O2 | 0.6769 (2) | 0.74894 (18) | 0.35525 (12) | 0.0628 (5) | |
O3 | 0.84268 (18) | 1.11035 (16) | 0.20498 (10) | 0.0505 (4) | |
H3 | 0.9224 | 1.0682 | 0.1745 | 0.076* | |
O4 | 0.81830 (19) | 1.0557 (2) | 0.40909 (11) | 0.0585 (4) | |
O5 | 0.59099 (18) | 0.9737 (2) | 0.13823 (10) | 0.0548 (4) | |
O6 | 1.12695 (19) | 1.01733 (17) | 0.10655 (11) | 0.0546 (4) | |
Atomic displacement parameters (Å2) top | U11 | U22 | U33 | U12 | U13 | U23 |
C1 | 0.0529 (13) | 0.0890 (19) | 0.0538 (13) | −0.0006 (12) | −0.0108 (11) | −0.0089 (12) |
C2 | 0.0587 (14) | 0.0959 (19) | 0.0438 (12) | −0.0003 (13) | −0.0166 (10) | −0.0064 (12) |
C3 | 0.0543 (12) | 0.0673 (14) | 0.0346 (10) | −0.0112 (10) | −0.0086 (8) | −0.0046 (9) |
C4 | 0.0412 (10) | 0.0438 (10) | 0.0358 (9) | −0.0108 (8) | −0.0031 (7) | −0.0044 (7) |
C5 | 0.0387 (9) | 0.0356 (9) | 0.0318 (8) | −0.0095 (7) | −0.0018 (7) | −0.0042 (7) |
C6 | 0.0398 (9) | 0.0429 (10) | 0.0326 (9) | −0.0087 (7) | −0.0019 (7) | −0.0072 (7) |
C7 | 0.0400 (9) | 0.0422 (10) | 0.0307 (9) | −0.0093 (7) | −0.0004 (7) | −0.0035 (7) |
C8 | 0.0415 (10) | 0.0386 (9) | 0.0346 (9) | −0.0074 (7) | −0.0025 (7) | −0.0042 (7) |
C9 | 0.0834 (19) | 0.0390 (12) | 0.102 (2) | −0.0200 (12) | 0.0149 (16) | 0.0000 (12) |
C10 | 0.0404 (9) | 0.0355 (9) | 0.0348 (9) | −0.0101 (7) | −0.0005 (7) | −0.0030 (7) |
C11 | 0.0503 (11) | 0.0330 (9) | 0.0391 (9) | −0.0104 (8) | −0.0041 (8) | −0.0058 (7) |
C12 | 0.0492 (11) | 0.0351 (9) | 0.0366 (9) | −0.0063 (8) | −0.0004 (8) | −0.0039 (7) |
C13 | 0.0653 (14) | 0.0570 (13) | 0.0432 (11) | −0.0002 (11) | 0.0015 (10) | −0.0135 (9) |
C14 | 0.0637 (16) | 0.091 (2) | 0.0602 (15) | 0.0097 (14) | 0.0117 (12) | −0.0242 (14) |
C15 | 0.0462 (13) | 0.106 (2) | 0.0758 (18) | 0.0109 (14) | −0.0003 (12) | −0.0217 (16) |
C16 | 0.0457 (12) | 0.0700 (15) | 0.0581 (13) | 0.0014 (10) | −0.0079 (10) | −0.0134 (11) |
C17 | 0.0452 (10) | 0.0383 (9) | 0.0396 (10) | −0.0045 (8) | −0.0009 (8) | −0.0036 (7) |
C18 | 0.0436 (10) | 0.0362 (9) | 0.0355 (9) | −0.0060 (7) | −0.0027 (7) | −0.0017 (7) |
C19 | 0.0402 (10) | 0.0434 (10) | 0.0373 (9) | −0.0104 (8) | −0.0010 (7) | −0.0034 (8) |
C20 | 0.0384 (9) | 0.0449 (10) | 0.0350 (9) | −0.0060 (8) | −0.0049 (7) | −0.0041 (7) |
C21 | 0.0457 (11) | 0.0600 (13) | 0.0359 (10) | −0.0059 (9) | 0.0004 (8) | −0.0083 (9) |
C22 | 0.0491 (12) | 0.0601 (13) | 0.0481 (11) | −0.0049 (10) | −0.0053 (9) | −0.0213 (10) |
C23 | 0.0600 (13) | 0.0461 (11) | 0.0577 (13) | −0.0127 (10) | −0.0067 (10) | −0.0144 (9) |
C24 | 0.0582 (13) | 0.0453 (11) | 0.0480 (11) | −0.0140 (9) | −0.0003 (9) | −0.0048 (9) |
C25 | 0.0397 (9) | 0.0439 (10) | 0.0349 (9) | −0.0067 (8) | −0.0031 (7) | −0.0053 (7) |
N1 | 0.0459 (9) | 0.0622 (11) | 0.0323 (8) | 0.0022 (8) | −0.0059 (7) | −0.0060 (7) |
N2 | 0.0496 (9) | 0.0455 (9) | 0.0387 (8) | −0.0122 (7) | 0.0075 (7) | 0.0007 (7) |
O1 | 0.0625 (10) | 0.0351 (8) | 0.0840 (12) | −0.0101 (7) | 0.0187 (8) | −0.0054 (7) |
O2 | 0.0667 (10) | 0.0445 (8) | 0.0712 (11) | −0.0118 (7) | 0.0295 (8) | −0.0054 (7) |
O3 | 0.0534 (8) | 0.0365 (7) | 0.0585 (9) | −0.0110 (6) | 0.0104 (7) | 0.0016 (6) |
O4 | 0.0596 (10) | 0.0674 (10) | 0.0518 (9) | −0.0111 (8) | −0.0131 (7) | −0.0219 (7) |
O5 | 0.0517 (8) | 0.0725 (10) | 0.0395 (7) | −0.0074 (7) | −0.0060 (6) | −0.0151 (7) |
O6 | 0.0616 (9) | 0.0419 (8) | 0.0604 (9) | −0.0159 (7) | 0.0137 (7) | −0.0092 (7) |
Geometric parameters (Å, º) top
C1—N1 | 1.418 (3) | C10—C11 | 1.552 (3) |
C1—C2 | 1.530 (3) | C11—O4 | 1.207 (2) |
C1—H1A | 0.970 | C11—C12 | 1.481 (3) |
C1—H1B | 0.970 | C12—C13 | 1.385 (3) |
C2—C3 | 1.538 (3) | C12—C17 | 1.391 (3) |
C2—H2A | 0.970 | C13—C14 | 1.380 (4) |
C2—H2B | 0.970 | C13—H13 | 0.930 |
C3—C4 | 1.527 (3) | C14—C15 | 1.389 (4) |
C3—H3A | 0.970 | C14—H14 | 0.930 |
C3—H3B | 0.970 | C15—C16 | 1.376 (3) |
C4—N1 | 1.454 (2) | C15—H15 | 0.930 |
C4—C5 | 1.563 (3) | C16—C17 | 1.387 (3) |
C4—H4 | 0.980 | C16—H16 | 0.930 |
C5—C8 | 1.520 (3) | C17—C18 | 1.470 (3) |
C5—C10 | 1.554 (3) | C18—O5 | 1.212 (2) |
C5—C6 | 1.565 (2) | C19—O6 | 1.227 (2) |
C6—C7 | 1.549 (3) | C19—N2 | 1.342 (2) |
C6—H6A | 0.970 | C20—C21 | 1.378 (3) |
C6—H6B | 0.970 | C20—C25 | 1.386 (3) |
C7—N1 | 1.443 (2) | C20—N2 | 1.413 (3) |
C7—C25 | 1.508 (3) | C21—C22 | 1.380 (3) |
C7—C19 | 1.547 (3) | C21—H21 | 0.930 |
C8—O2 | 1.194 (2) | C22—C23 | 1.383 (3) |
C8—O1 | 1.321 (2) | C22—H22 | 0.930 |
C9—O1 | 1.437 (3) | C23—C24 | 1.392 (3) |
C9—H9A | 0.960 | C23—H23 | 0.930 |
C9—H9B | 0.960 | C24—C25 | 1.375 (3) |
C9—H9C | 0.960 | C24—H24 | 0.930 |
C10—O3 | 1.416 (2) | N2—H2 | 0.860 |
C10—C18 | 1.549 (3) | O3—H3 | 0.820 |
| | | |
N1—C1—C2 | 102.9 (2) | C18—C10—C5 | 113.37 (14) |
N1—C1—H1A | 111.2 | C11—C10—C5 | 115.28 (14) |
C2—C1—H1A | 111.2 | O4—C11—C12 | 126.58 (18) |
N1—C1—H1B | 111.2 | O4—C11—C10 | 124.95 (18) |
C2—C1—H1B | 111.2 | C12—C11—C10 | 108.28 (15) |
H1A—C1—H1B | 109.1 | C13—C12—C17 | 120.60 (19) |
C1—C2—C3 | 107.13 (18) | C13—C12—C11 | 129.30 (19) |
C1—C2—H2A | 110.3 | C17—C12—C11 | 110.09 (16) |
C3—C2—H2A | 110.3 | C14—C13—C12 | 117.8 (2) |
C1—C2—H2B | 110.3 | C14—C13—H13 | 121.1 |
C3—C2—H2B | 110.3 | C12—C13—H13 | 121.1 |
H2A—C2—H2B | 108.5 | C13—C14—C15 | 121.5 (2) |
C4—C3—C2 | 101.48 (17) | C13—C14—H14 | 119.3 |
C4—C3—H3A | 111.5 | C15—C14—H14 | 119.3 |
C2—C3—H3A | 111.5 | C16—C15—C14 | 121.0 (2) |
C4—C3—H3B | 111.5 | C16—C15—H15 | 119.5 |
C2—C3—H3B | 111.5 | C14—C15—H15 | 119.5 |
H3A—C3—H3B | 109.3 | C15—C16—C17 | 117.8 (2) |
N1—C4—C3 | 101.26 (16) | C15—C16—H16 | 121.1 |
N1—C4—C5 | 102.98 (14) | C17—C16—H16 | 121.1 |
C3—C4—C5 | 125.42 (16) | C16—C17—C12 | 121.35 (19) |
N1—C4—H4 | 108.6 | C16—C17—C18 | 128.16 (19) |
C3—C4—H4 | 108.6 | C12—C17—C18 | 110.47 (17) |
C5—C4—H4 | 108.6 | O5—C18—C17 | 125.98 (18) |
C8—C5—C10 | 107.67 (14) | O5—C18—C10 | 125.24 (17) |
C8—C5—C4 | 111.37 (14) | C17—C18—C10 | 108.65 (15) |
C10—C5—C4 | 111.77 (14) | O6—C19—N2 | 126.15 (18) |
C8—C5—C6 | 110.70 (14) | O6—C19—C7 | 125.72 (17) |
C10—C5—C6 | 112.21 (14) | N2—C19—C7 | 108.11 (16) |
C4—C5—C6 | 103.16 (14) | C21—C20—C25 | 122.21 (19) |
C7—C6—C5 | 107.37 (14) | C21—C20—N2 | 129.03 (18) |
C7—C6—H6A | 110.2 | C25—C20—N2 | 108.76 (16) |
C5—C6—H6A | 110.2 | C20—C21—C22 | 117.4 (2) |
C7—C6—H6B | 110.2 | C20—C21—H21 | 121.3 |
C5—C6—H6B | 110.2 | C22—C21—H21 | 121.3 |
H6A—C6—H6B | 108.5 | C21—C22—C23 | 121.3 (2) |
N1—C7—C25 | 114.21 (15) | C21—C22—H22 | 119.3 |
N1—C7—C19 | 115.15 (15) | C23—C22—H22 | 119.3 |
C25—C7—C19 | 101.53 (14) | C22—C23—C24 | 120.5 (2) |
N1—C7—C6 | 101.33 (14) | C22—C23—H23 | 119.8 |
C25—C7—C6 | 115.80 (15) | C24—C23—H23 | 119.8 |
C19—C7—C6 | 109.32 (15) | C25—C24—C23 | 118.6 (2) |
O2—C8—O1 | 122.84 (18) | C25—C24—H24 | 120.7 |
O2—C8—C5 | 123.76 (17) | C23—C24—H24 | 120.7 |
O1—C8—C5 | 113.39 (16) | C24—C25—C20 | 119.92 (18) |
O1—C9—H9A | 109.5 | C24—C25—C7 | 130.73 (18) |
O1—C9—H9B | 109.5 | C20—C25—C7 | 109.35 (16) |
H9A—C9—H9B | 109.5 | C1—N1—C7 | 128.3 (2) |
O1—C9—H9C | 109.5 | C1—N1—C4 | 109.7 (2) |
H9A—C9—H9C | 109.5 | C7—N1—C4 | 110.7 (2) |
H9B—C9—H9C | 109.5 | C19—N2—C20 | 112.15 (16) |
O3—C10—C18 | 105.84 (14) | C19—N2—H2 | 123.9 |
O3—C10—C11 | 105.52 (14) | C20—N2—H2 | 123.9 |
C18—C10—C11 | 102.21 (14) | C8—O1—C9 | 116.70 (18) |
O3—C10—C5 | 113.51 (15) | C10—O3—H3 | 109.5 |
| | | |
N1—C1—C2—C3 | −5.1 (3) | C16—C17—C18—O5 | 2.1 (4) |
C1—C2—C3—C4 | −19.6 (3) | C12—C17—C18—O5 | −179.30 (19) |
C2—C3—C4—N1 | 36.2 (2) | C16—C17—C18—C10 | 178.2 (2) |
C2—C3—C4—C5 | 151.2 (2) | C12—C17—C18—C10 | −3.1 (2) |
N1—C4—C5—C8 | 97.01 (17) | O3—C10—C18—O5 | 71.0 (2) |
C3—C4—C5—C8 | −17.2 (3) | C11—C10—C18—O5 | −178.76 (19) |
N1—C4—C5—C10 | −142.52 (15) | C5—C10—C18—O5 | −54.1 (2) |
C3—C4—C5—C10 | 103.3 (2) | O3—C10—C18—C17 | −105.22 (16) |
N1—C4—C5—C6 | −21.76 (18) | C11—C10—C18—C17 | 5.02 (18) |
C3—C4—C5—C6 | −135.95 (19) | C5—C10—C18—C17 | 129.73 (16) |
C8—C5—C6—C7 | −118.80 (16) | N1—C7—C19—O6 | −59.6 (3) |
C10—C5—C6—C7 | 120.89 (16) | C25—C7—C19—O6 | 176.44 (19) |
C4—C5—C6—C7 | 0.43 (18) | C6—C7—C19—O6 | 53.6 (2) |
C5—C6—C7—N1 | 21.09 (18) | N1—C7—C19—N2 | 121.96 (17) |
C5—C6—C7—C25 | 145.24 (15) | C25—C7—C19—N2 | −1.97 (19) |
C5—C6—C7—C19 | −100.88 (16) | C6—C7—C19—N2 | −124.80 (16) |
C10—C5—C8—O2 | −13.5 (2) | C25—C20—C21—C22 | −1.7 (3) |
C4—C5—C8—O2 | 109.4 (2) | N2—C20—C21—C22 | 177.90 (19) |
C6—C5—C8—O2 | −136.4 (2) | C20—C21—C22—C23 | 0.7 (3) |
C10—C5—C8—O1 | 166.54 (16) | C21—C22—C23—C24 | 0.9 (3) |
C4—C5—C8—O1 | −70.6 (2) | C22—C23—C24—C25 | −1.5 (3) |
C6—C5—C8—O1 | 43.6 (2) | C23—C24—C25—C20 | 0.5 (3) |
C8—C5—C10—O3 | −178.80 (14) | C23—C24—C25—C7 | 179.97 (19) |
C4—C5—C10—O3 | 58.59 (19) | C21—C20—C25—C24 | 1.1 (3) |
C6—C5—C10—O3 | −56.7 (2) | N2—C20—C25—C24 | −178.57 (17) |
C8—C5—C10—C18 | −57.98 (18) | C21—C20—C25—C7 | −178.46 (17) |
C4—C5—C10—C18 | 179.40 (14) | N2—C20—C25—C7 | 1.9 (2) |
C6—C5—C10—C18 | 64.08 (19) | N1—C7—C25—C24 | 55.9 (3) |
C8—C5—C10—C11 | 59.33 (19) | C19—C7—C25—C24 | −179.5 (2) |
C4—C5—C10—C11 | −63.3 (2) | C6—C7—C25—C24 | −61.2 (3) |
C6—C5—C10—C11 | −178.61 (14) | N1—C7—C25—C20 | −124.55 (18) |
O3—C10—C11—O4 | −70.1 (2) | C19—C7—C25—C20 | 0.01 (19) |
C18—C10—C11—O4 | 179.44 (18) | C6—C7—C25—C20 | 118.28 (17) |
C5—C10—C11—O4 | 56.0 (3) | C2—C1—N1—C7 | 169.9 (2) |
O3—C10—C11—C12 | 105.26 (16) | C2—C1—N1—C4 | 30.4 (3) |
C18—C10—C11—C12 | −5.23 (18) | C25—C7—N1—C1 | 57.8 (3) |
C5—C10—C11—C12 | −128.66 (16) | C19—C7—N1—C1 | −59.1 (3) |
O4—C11—C12—C13 | −1.8 (3) | C6—C7—N1—C1 | −176.9 (2) |
C10—C11—C12—C13 | −177.1 (2) | C25—C7—N1—C4 | −163.00 (16) |
O4—C11—C12—C17 | 179.0 (2) | C19—C7—N1—C4 | 80.0 (2) |
C10—C11—C12—C17 | 3.7 (2) | C6—C7—N1—C4 | −37.8 (2) |
C17—C12—C13—C14 | 1.0 (3) | C3—C4—N1—C1 | −43.5 (2) |
C11—C12—C13—C14 | −178.2 (2) | C5—C4—N1—C1 | −174.23 (18) |
C12—C13—C14—C15 | −0.4 (4) | C3—C4—N1—C7 | 169.51 (17) |
C13—C14—C15—C16 | −0.3 (5) | C5—C4—N1—C7 | 38.8 (2) |
C14—C15—C16—C17 | 0.4 (5) | O6—C19—N2—C20 | −175.11 (19) |
C15—C16—C17—C12 | 0.2 (4) | C7—C19—N2—C20 | 3.3 (2) |
C15—C16—C17—C18 | 178.7 (2) | C21—C20—N2—C19 | 177.01 (19) |
C13—C12—C17—C16 | −0.9 (3) | C25—C20—N2—C19 | −3.3 (2) |
C11—C12—C17—C16 | 178.36 (19) | O2—C8—O1—C9 | 1.7 (3) |
C13—C12—C17—C18 | −179.68 (18) | C5—C8—O1—C9 | −178.3 (2) |
C11—C12—C17—C18 | −0.4 (2) | | |
Hydrogen-bond geometry (Å, º) top
D—H···A | D—H | H···A | D···A | D—H···A |
O3—H3···O6 | 0.82 | 1.94 | 2.739 (2) | 166 |
N2—H2···O5i | 0.86 | 2.19 | 3.048 (2) | 173 |
Symmetry code: (i) −x+2, −y+2, −z. |
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