(1S,3R,8R,9S,11R)-2,2,10,10-Tetra­chloro-3,7,7,11-tetra­methyl­tetra­cyclo­[6.5.0.01,3.09,11]trideca­ne

Ourhriss, N.; Benharref, A.; Saadi, M.; El Ammari, L.; Berraho, M.

doi:10.1107/S1600536813001700

organic compounds

CRYSTALLOGRAPHIC
COMMUNICATIONS

ISSN: 2056-9890

Volume 69| Part 2| February 2013| Page o275

doi:10.1107/S1600536813001700

Open

access

(1S,3R,8R,9S,11R)-2,2,10,10-Tetrachloro-3,7,7,11-tetramethyltetracyclo[6.5.0.0^1,3.0^9,11]tridecane

Najia Ourhriss,^a ^* Ahmed Benharref,^a Mohamed Saadi,^b Lahcen El Ammari ^b and Moha Berraho ^a

^aLaboratoire de Chimie Biomoléculaire, Substances Naturelles et Réactivité "Unité Associée au CNRST(URAC16)", Faculté des Sciences Semlalia, BP 2390, Bd My Abdellah, 40000 Marrakech, Morocco, and ^bLaboratoire de Chimie du Solide Appliquée, Faculté des Sciences, Avenue Ibn Battouta, BP 1014 Rabat, Morocco
^*Correspondence e-mail: berraho@uca.ma

(Received 14 January 2013; accepted 16 January 2013; online 23 January 2013)

The title compound, C₁₇H₂₄Cl₄, was synthesized from β-himachalene (3,5,5,9-tetramethyl-2,4a,5,6,7,8-hexahydro-1H-benzocycloheptene), which was isolated from the essential oil of the Atlas cedar (Cedrus Atlantica). The molecule is built up from fused six- and seven-membered rings and two three-membered rings from the reaction of β-himachalene with dichlorocarbene. The six-membered ring shows a chair conformation, whereas the seven-membered ring displays a boat conformation.

Related literature

For the isolation of β-himachalene, see: Joseph & Dev (1968 ); Plattier & Teisseire (1974 ). For the reactivity of this sesquiterpene, see: Lassaba et al. (1998 ); Chekroun et al. (2000 ); El Jamili et al. (2002 ); Sbai et al. (2002 ); Dakir et al. (2004 ). For its biological activity, see: Daoubi et al. (2004 ). For puckering parameters, see: Cremer & Pople (1975 ).

Experimental

Crystal data

C₁₇H₂₄Cl₄
M_r = 370.16
Monoclinic, P 2₁
a = 8.8807 (6) Å
b = 11.6280 (8) Å
c = 9.0596 (6) Å
β = 107.665 (2)°
V = 891.42 (10) Å³
Z = 2
Mo Kα radiation
μ = 0.66 mm⁻¹
T = 296 K
0.41 × 0.35 × 0.27 mm

Data collection

Bruker X8 APEX diffractometer
15112 measured reflections
5419 independent reflections
4910 reflections with I > 2σ(I)
R_int = 0.019

Refinement

R[F² > 2σ(F²)] = 0.032
wR(F²) = 0.085
S = 1.03
5419 reflections
190 parameters
1 restraint
H-atom parameters constrained
Δρ_max = 0.32 e Å⁻³
Δρ_min = −0.19 e Å⁻³
Absolute structure: Flack (1983 )
Flack parameter: 0.04 (4)

Data collection: APEX2 (Bruker, 2009 ); cell refinement: SAINT (Bruker, 2009); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008 ); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: ORTEP-3 for Windows (Farrugia, 2012 ); software used to prepare material for publication: PLATON (Spek, 2009 ) and publCIF (Westrip, 2010 ).

Supporting information

Crystal structure: contains datablocks I, global. DOI: 10.1107/S1600536813001700/bt6883sup1.cif

Structure factors: contains datablock I. DOI: 10.1107/S1600536813001700/bt6883Isup2.hkl

Supporting information file. DOI: 10.1107/S1600536813001700/bt6883Isup3.cml

checkCIF report

Comment top

The bicyclic sesquiterpene, β-himachalene is the main constituent (50%) of the essential oil of the Atlas cedar (Cedrus atlantica) (Joseph & Dev, 1968; Plattier & Teisseire, 1974). The reactivity of this sesquiterpene and its derivatives has been studied extensively by our team in order to prepare new products having biological proprieties (Lassaba et al., 1998; Chekroun et al., 2000; El Jamili et al., 2002; Sbai et al., 2002; Dakir et al., 2004). Indeed, these compounds were tested, using the food poisoning technique, for their potential antifungal activity against phytopathogen Botrytis cinerea (Daoubi et al., 2004). Thus the action of two equivalents of dichlorocarbene, generated in situ from chloroform in the presence of sodium hydroxide as base and n-benzyltriethylammonium chloride as catalyst, on β-himachalene leads to a mixture of two diastereisomers: (1S,3R,8R,9S,11R)-2,2,10,10-tetrachloro-3,7,7,11-tetraméthyletetracyclo [6,5,0,01.2,09.11] tridecane (X) and its isomer (1S,3R,8R,9R,11S)-2,2,10,10- tetrachloro-3,7,7,11-tetraméthyletetracyclo [6,5,0,01.2,09.11]tridecane (Y), in an over-all yield of 80% and 85/15 ratio. By single-crystal X-ray diffraction analysis, we have determined the absolute configuration of X and we deduced that from its isomer Y.

The molecule contains a fused six- and seven-membered rings, which is fused to two three-membered rings as schown in Fig. 1. The six-membered ring has a chair conformation, with as indicated by the total puckering amplitude QT = 0.4518 (19) Å and spherical polar angle θ = 140.4 (2)° with ϕ2 = 141.5 (4)°, whereas the seven-membered ring displays a boat conformation with QT = 1.1323 (2) Å, θ2 = 87.3 (1), ϕ2 = -48.94 (9)° and ϕ3 = -125 (2)° (Cremer & Pople, 1975). The dihedral angle between the five- and seven-membered rings is 55.89 (9)°. The three-membered ring (C1, C2, C3) ring is nearly perpendicular to the six-membered ring (C1, C8, C9, C11, C12, C13) with a dihedral angle of 84.24 (19)°. Owing to the presence of Cl atoms, the absolute configuration could be determined from anomalous dispersion effects, by refining the Flack parameter (Flack, 1983) as C1(S), C3(R), C8(R), C9(S), and C11(R).

Related literature top

For the isolation of β-himachalene, see: Joseph & Dev (1968); Plattier & Teisseire (1974). For the reactivity of this sesquiterpene, see: Lassaba et al. (1998); Chekroun et al. (2000); El Jamili et al. (2002); Sbai et al. (2002); Dakir et al. (2004). For its biological activity, see: Daoubi et al. (2004). For puckering parameters, see: Cremer & Pople (1975).

Experimental top

A solution containing 6 g (29 mmol) of β-himachalene and 6 mL (75 mmol) of CHCl₃ in 40 ml of dichloromethane was added dropwise at 273 K over 30 min to 1.6 g (40 mmol) of pulverized sodium hydroxide and 60 mg of N–benzyltriethylammonium chloride placed in a 100 ml three–necked flask. After stirring at room temperature for 2 h, the mixture was filtered on celite and concentrated in vacuum. The residue obtained was chromatographed on silicagel column impregnated with silver nitrate (10%) with a mixture of hexane - ethyl acetate (98–2) used as eluent. The two diastereoisomers (1S,3R,8R,9S,11R)-2,2,10,10-tetrachloro-3,7,7,11-tetraméthyletetracyclo [6,5,0,01.2,09.11] tridecane (X) and (1S,3R,8R,9R,11S)-2,2,10,10-tetrachloro-3,7,7,11-tetraméthyletetracyclo [6,5,0,01.2,09.11]tridecane (Y), were obtained by this procedure in a 85/15 ratio and a combined yield of 80% (8,5 g; 23,2 mmol). The title compound (isomer X) was recrystallized from pentane.

Computing details top

Data collection: APEX2 (Bruker, 2009); cell refinement: SAINT (Bruker, 2009); data reduction: SAINT (Bruker, 2009); program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: ORTEP-3 for Windows (Farrugia, 2012); software used to prepare material for publication: PLATON (Spek, 2009) and publCIF (Westrip, 2010).

Figures top

Fig. 1. : Molecular structure of the title compound with the atom-labelling scheme. Displacement ellipsoids are drawn at the 50% probability. level. H atoms are represented as small spheres of arbitrary radii.

(1S,3R,8R,9S,11R)-2,2,10,10-Tetrachloro-3,7,7,11-tetramethyltetracyclo[6.5.0.0^1,3.0^9,11]tridecane top

Crystal data top

C₁₇H₂₄Cl₄	F(000) = 388
M_r = 370.16	D_x = 1.379 Mg m⁻³
Monoclinic, P2₁	Mo Kα radiation, λ = 0.71073 Å
Hall symbol: P 2yb	Cell parameters from 5419 reflections
a = 8.8807 (6) Å	θ = 2.8–30.5°
b = 11.6280 (8) Å	µ = 0.66 mm⁻¹
c = 9.0596 (6) Å	T = 296 K
β = 107.665 (2)°	Block, colourless
V = 891.42 (10) Å³	0.41 × 0.35 × 0.27 mm
Z = 2

Data collection top

Bruker X8 APEX diffractometer	4910 reflections with I > 2σ(I)
Radiation source: fine-focus sealed tube	R_int = 0.019
Graphite monochromator	θ_max = 30.5°, θ_min = 2.8°
ϕ and ω scans	h = −12→12
15112 measured reflections	k = −16→16
5419 independent reflections	l = −12→12

Refinement top

Refinement on F²	Secondary atom site location: difference Fourier map
Least-squares matrix: full	Hydrogen site location: inferred from neighbouring sites
R[F² > 2σ(F²)] = 0.032	H-atom parameters constrained
wR(F²) = 0.085	w = 1/[σ²(F_o²) + (0.0491P)² + 0.074P] where P = (F_o² + 2F_c²)/3
S = 1.03	(Δ/σ)_max = 0.001
5419 reflections	Δρ_max = 0.32 e Å⁻³
190 parameters	Δρ_min = −0.19 e Å⁻³
1 restraint	Absolute structure: Flack (1983)
Primary atom site location: structure-invariant direct methods	Absolute structure parameter: 0.04 (4)

Crystal data top

C₁₇H₂₄Cl₄	V = 891.42 (10) Å³
M_r = 370.16	Z = 2
Monoclinic, P2₁	Mo Kα radiation
a = 8.8807 (6) Å	µ = 0.66 mm⁻¹
b = 11.6280 (8) Å	T = 296 K
c = 9.0596 (6) Å	0.41 × 0.35 × 0.27 mm
β = 107.665 (2)°

Data collection top

Bruker X8 APEX diffractometer	4910 reflections with I > 2σ(I)
15112 measured reflections	R_int = 0.019
5419 independent reflections

Refinement top

R[F² > 2σ(F²)] = 0.032	H-atom parameters constrained
wR(F²) = 0.085	Δρ_max = 0.32 e Å⁻³
S = 1.03	Δρ_min = −0.19 e Å⁻³
5419 reflections	Absolute structure: Flack (1983)
190 parameters	Absolute structure parameter: 0.04 (4)
1 restraint

Special details top

Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes.

Refinement. Refinement of F² against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F², conventional R-factors R are based on F, with F set to zero for negative F². The threshold expression of F² > σ(F²) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F² are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger.

Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å²) top

	x	y	z	U_iso*/U_eq
Cl1	0.38317 (6)	0.32772 (6)	0.92294 (6)	0.06701 (17)
Cl2	0.52164 (6)	0.12723 (5)	0.83384 (6)	0.05443 (13)
Cl3	0.78628 (6)	0.23092 (5)	1.13768 (5)	0.05374 (13)
Cl4	1.12169 (5)	0.25246 (4)	1.19453 (5)	0.04960 (12)
C1	0.62379 (15)	0.35612 (13)	0.77816 (16)	0.0288 (3)
C2	0.49711 (18)	0.27743 (16)	0.80650 (18)	0.0391 (4)
C3	0.47133 (16)	0.32604 (17)	0.64690 (18)	0.0380 (3)
C4	0.48758 (19)	0.24243 (18)	0.52377 (18)	0.0431 (4)
H4A	0.5552	0.1791	0.5733	0.052*
H4B	0.3845	0.2111	0.4692	0.052*
C5	0.5566 (2)	0.2997 (2)	0.40815 (19)	0.0518 (5)
H5A	0.4729	0.3396	0.3311	0.062*
H5B	0.5980	0.2408	0.3552	0.062*
C6	0.6879 (2)	0.38477 (18)	0.48244 (18)	0.0442 (4)
H6A	0.6393	0.4506	0.5156	0.053*
H6B	0.7306	0.4116	0.4019	0.053*
C7	0.82871 (16)	0.34716 (14)	0.62113 (16)	0.0324 (3)
C8	0.77955 (14)	0.30517 (11)	0.76794 (14)	0.0244 (2)
H8	0.7717	0.2249	0.7579	0.029*
C9	0.91820 (15)	0.32805 (12)	0.91322 (15)	0.0269 (2)
H9	1.0184	0.3143	0.8884	0.032*
C10	0.93290 (17)	0.29978 (13)	1.07857 (15)	0.0317 (3)
C11	0.91735 (18)	0.42382 (14)	1.02843 (17)	0.0350 (3)
C12	0.7581 (2)	0.48145 (17)	1.0110 (2)	0.0474 (4)
H12A	0.7766	0.5613	1.0420	0.057*
H12B	0.7095	0.4446	1.0812	0.057*
C13	0.64262 (19)	0.47670 (14)	0.84681 (19)	0.0377 (3)
H13A	0.5402	0.5044	0.8488	0.045*
H13B	0.6798	0.5277	0.7806	0.045*
C14	0.3446 (2)	0.4161 (2)	0.5839 (2)	0.0545 (5)
H14A	0.3648	0.4816	0.6516	0.082*
H14B	0.2430	0.3844	0.5775	0.082*
H14C	0.3457	0.4395	0.4826	0.082*
C15	0.9169 (2)	0.2471 (2)	0.57360 (19)	0.0469 (4)
H15A	0.8513	0.1798	0.5550	0.070*
H15B	1.0128	0.2318	0.6552	0.070*
H15C	0.9418	0.2672	0.4809	0.070*
C16	0.9411 (2)	0.45147 (18)	0.6573 (2)	0.0459 (4)
H16A	1.0290	0.4353	0.7471	0.069*
H16B	0.8854	0.5177	0.6767	0.069*
H16C	0.9789	0.4664	0.5704	0.069*
C17	1.0594 (2)	0.50220 (16)	1.0855 (2)	0.0529 (5)
H17A	1.0320	0.5781	1.0443	0.079*
H17B	1.1446	0.4729	1.0518	0.079*
H17C	1.0917	0.5053	1.1967	0.079*

Atomic displacement parameters (Å²) top

	U¹¹	U²²	U³³	U¹²	U¹³	U²³
Cl1	0.0372 (2)	0.1166 (5)	0.0572 (3)	0.0018 (3)	0.0294 (2)	−0.0039 (3)
Cl2	0.0510 (2)	0.0575 (3)	0.0527 (3)	−0.0213 (2)	0.0126 (2)	0.0075 (2)
Cl3	0.0529 (2)	0.0783 (3)	0.03199 (18)	−0.0149 (2)	0.01578 (16)	0.00474 (19)
Cl4	0.0432 (2)	0.0512 (2)	0.03845 (19)	0.00492 (18)	−0.01151 (15)	0.00149 (18)
C1	0.0203 (5)	0.0383 (7)	0.0276 (6)	0.0004 (5)	0.0068 (5)	−0.0003 (5)
C2	0.0253 (6)	0.0579 (10)	0.0358 (7)	−0.0060 (6)	0.0120 (5)	−0.0007 (7)
C3	0.0202 (6)	0.0576 (10)	0.0339 (7)	−0.0013 (6)	0.0046 (5)	0.0000 (7)
C4	0.0305 (7)	0.0607 (10)	0.0318 (7)	−0.0065 (7)	−0.0001 (5)	−0.0055 (7)
C5	0.0408 (8)	0.0849 (15)	0.0247 (7)	−0.0039 (9)	0.0024 (6)	−0.0019 (8)
C6	0.0364 (8)	0.0666 (12)	0.0288 (7)	0.0003 (7)	0.0089 (6)	0.0111 (7)
C7	0.0268 (6)	0.0455 (8)	0.0260 (6)	−0.0005 (6)	0.0095 (5)	0.0001 (6)
C8	0.0209 (5)	0.0299 (6)	0.0212 (5)	0.0004 (5)	0.0049 (4)	−0.0022 (5)
C9	0.0220 (5)	0.0327 (6)	0.0244 (6)	0.0006 (5)	0.0048 (4)	−0.0024 (5)
C10	0.0295 (6)	0.0385 (7)	0.0234 (6)	0.0007 (6)	0.0023 (5)	−0.0018 (5)
C11	0.0321 (7)	0.0350 (7)	0.0317 (7)	0.0009 (6)	0.0006 (5)	−0.0070 (6)
C12	0.0456 (9)	0.0486 (9)	0.0434 (9)	0.0131 (7)	0.0066 (7)	−0.0172 (7)
C13	0.0319 (7)	0.0384 (8)	0.0412 (8)	0.0100 (6)	0.0087 (6)	−0.0023 (6)
C14	0.0264 (7)	0.0793 (14)	0.0513 (10)	0.0126 (8)	0.0020 (7)	0.0039 (10)
C15	0.0433 (8)	0.0676 (11)	0.0341 (7)	0.0100 (8)	0.0184 (6)	−0.0059 (8)
C16	0.0372 (8)	0.0578 (11)	0.0453 (9)	−0.0095 (7)	0.0162 (7)	0.0063 (8)
C17	0.0513 (10)	0.0410 (9)	0.0527 (10)	−0.0117 (8)	−0.0050 (8)	−0.0085 (8)

Geometric parameters (Å, º) top

Cl1—C2	1.7682 (17)	C8—H8	0.9380
Cl2—C2	1.768 (2)	C9—C10	1.5001 (19)
Cl3—C10	1.7454 (16)	C9—C11	1.528 (2)
Cl4—C10	1.7744 (14)	C9—H9	0.9951
C1—C13	1.522 (2)	C10—C11	1.506 (2)
C1—C2	1.531 (2)	C11—C17	1.515 (2)
C1—C8	1.5332 (17)	C11—C12	1.529 (2)
C1—C3	1.5468 (19)	C12—C13	1.530 (2)
C2—C3	1.504 (2)	C12—H12A	0.9700
C3—C14	1.517 (2)	C12—H12B	0.9700
C3—C4	1.519 (2)	C13—H13A	0.9700
C4—C5	1.519 (3)	C13—H13B	0.9700
C4—H4A	0.9700	C14—H14A	0.9600
C4—H4B	0.9700	C14—H14B	0.9600
C5—C6	1.521 (3)	C14—H14C	0.9600
C5—H5A	0.9700	C15—H15A	0.9600
C5—H5B	0.9700	C15—H15B	0.9600
C6—C7	1.543 (2)	C15—H15C	0.9600
C6—H6A	0.9700	C16—H16A	0.9600
C6—H6B	0.9700	C16—H16B	0.9600
C7—C15	1.536 (2)	C16—H16C	0.9600
C7—C16	1.541 (2)	C17—H17A	0.9600
C7—C8	1.5970 (19)	C17—H17B	0.9600
C8—C9	1.5283 (17)	C17—H17C	0.9600

C13—C1—C2	118.50 (12)	C10—C9—H9	112.2
C13—C1—C8	113.04 (11)	C11—C9—H9	117.5
C2—C1—C8	120.10 (13)	C8—C9—H9	108.6
C13—C1—C3	118.97 (13)	C9—C10—C11	61.10 (10)
C2—C1—C3	58.50 (10)	C9—C10—Cl3	124.05 (10)
C8—C1—C3	117.48 (12)	C11—C10—Cl3	121.55 (11)
C3—C2—C1	61.28 (10)	C9—C10—Cl4	116.07 (10)
C3—C2—Cl2	118.84 (13)	C11—C10—Cl4	117.34 (11)
C1—C2—Cl2	123.25 (12)	Cl3—C10—Cl4	109.57 (8)
C3—C2—Cl1	120.10 (13)	C10—C11—C17	118.86 (14)
C1—C2—Cl1	119.01 (12)	C10—C11—C9	59.27 (9)
Cl2—C2—Cl1	108.16 (9)	C17—C11—C9	119.72 (15)
C2—C3—C14	120.05 (14)	C10—C11—C12	116.63 (15)
C2—C3—C4	116.41 (16)	C17—C11—C12	114.83 (15)
C14—C3—C4	112.99 (14)	C9—C11—C12	116.42 (12)
C2—C3—C1	60.23 (9)	C11—C12—C13	114.26 (13)
C14—C3—C1	120.64 (16)	C11—C12—H12A	108.7
C4—C3—C1	116.95 (12)	C13—C12—H12A	108.7
C5—C4—C3	111.97 (17)	C11—C12—H12B	108.7
C5—C4—H4A	109.2	C13—C12—H12B	108.7
C3—C4—H4A	109.2	H12A—C12—H12B	107.6
C5—C4—H4B	109.2	C1—C13—C12	112.86 (13)
C3—C4—H4B	109.2	C1—C13—H13A	109.0
H4A—C4—H4B	107.9	C12—C13—H13A	109.0
C4—C5—C6	113.30 (13)	C1—C13—H13B	109.0
C4—C5—H5A	108.9	C12—C13—H13B	109.0
C6—C5—H5A	108.9	H13A—C13—H13B	107.8
C4—C5—H5B	108.9	C3—C14—H14A	109.5
C6—C5—H5B	108.9	C3—C14—H14B	109.5
H5A—C5—H5B	107.7	H14A—C14—H14B	109.5
C5—C6—C7	119.92 (16)	C3—C14—H14C	109.5
C5—C6—H6A	107.3	H14A—C14—H14C	109.5
C7—C6—H6A	107.3	H14B—C14—H14C	109.5
C5—C6—H6B	107.3	C7—C15—H15A	109.5
C7—C6—H6B	107.3	C7—C15—H15B	109.5
H6A—C6—H6B	106.9	H15A—C15—H15B	109.5
C15—C7—C16	107.65 (13)	C7—C15—H15C	109.5
C15—C7—C6	110.06 (13)	H15A—C15—H15C	109.5
C16—C7—C6	105.23 (14)	H15B—C15—H15C	109.5
C15—C7—C8	107.07 (13)	C7—C16—H16A	109.5
C16—C7—C8	112.76 (12)	C7—C16—H16B	109.5
C6—C7—C8	113.95 (11)	H16A—C16—H16B	109.5
C9—C8—C1	112.74 (10)	C7—C16—H16C	109.5
C9—C8—C7	108.15 (10)	H16A—C16—H16C	109.5
C1—C8—C7	114.32 (11)	H16B—C16—H16C	109.5
C9—C8—H8	105.9	C11—C17—H17A	109.5
C1—C8—H8	110.4	C11—C17—H17B	109.5
C7—C8—H8	104.7	H17A—C17—H17B	109.5
C10—C9—C11	59.64 (10)	C11—C17—H17C	109.5
C10—C9—C8	128.69 (12)	H17A—C17—H17C	109.5
C11—C9—C8	123.06 (11)	H17B—C17—H17C	109.5

Experimental details

Crystal data
Chemical formula	C₁₇H₂₄Cl₄
M_r	370.16
Crystal system, space group	Monoclinic, P2₁
Temperature (K)	296
a, b, c (Å)	8.8807 (6), 11.6280 (8), 9.0596 (6)
β (°)	107.665 (2)
V (Å³)	891.42 (10)
Z	2
Radiation type	Mo Kα
µ (mm⁻¹)	0.66
Crystal size (mm)	0.41 × 0.35 × 0.27

Data collection
Diffractometer	Bruker X8 APEX diffractometer
Absorption correction	–
No. of measured, independent and observed [I > 2σ(I)] reflections	15112, 5419, 4910
R_int	0.019
(sin θ/λ)_max (Å⁻¹)	0.714

Refinement
R[F² > 2σ(F²)], wR(F²), S	0.032, 0.085, 1.03
No. of reflections	5419
No. of parameters	190
No. of restraints	1
H-atom treatment	H-atom parameters constrained
Δρ_max, Δρ_min (e Å⁻³)	0.32, −0.19
Absolute structure	Flack (1983)
Absolute structure parameter	0.04 (4)

Computer programs: APEX2 (Bruker, 2009), SAINT (Bruker, 2009), SHELXS97 (Sheldrick, 2008), SHELXL97 (Sheldrick, 2008), ORTEP-3 for Windows (Farrugia, 2012), PLATON (Spek, 2009) and publCIF (Westrip, 2010).

References

Bruker (2009). APEX2, SAINT and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA. Google Scholar
Chekroun, A., Jarid, A., Benharref, A. & Boutalib, A. (2000). J. Org. Chem. 65, 4431–4434. Web of Science CrossRef PubMed CAS Google Scholar
Cremer, D. & Pople, J. A. (1975). J. Am. Chem. Soc. 97, 1354–1358. CrossRef CAS Web of Science Google Scholar
Dakir, M., Auhmani, A., Ait Itto, M. Y., Mazoir, N., Akssira, M., Pierrot, M. & Benharref, A. (2004). Synth. Commun. 34, 2001–2008. Web of Science CrossRef CAS Google Scholar
Daoubi, M., Duran -Patron, R., Hmamouchi, M., Hernandez -Galan, R., Benharref, A. & Isidro, G. C. (2004). Pest Manag. Sci. 60, 927–932. Web of Science CrossRef PubMed CAS Google Scholar
El Jamili, H., Auhmani, A., Dakir, M., Lassaba, E., Benharref, A., Pierrot, M., Chiaroni, A. & Riche, C. (2002). Tetrahedron Lett. 43, 6645–6648. CAS Google Scholar
Farrugia, L. J. (2012). J. Appl. Cryst. 45, 849–854. Web of Science CrossRef CAS IUCr Journals Google Scholar
Flack, H. D. (1983). Acta Cryst. A39, 876–881. CrossRef CAS Web of Science IUCr Journals Google Scholar
Joseph, T. C. & Dev, S. (1968). Tetrahedron, 24, 3841–3859. CrossRef CAS Web of Science Google Scholar
Lassaba, E., Eljamili, H., Chekroun, A., Benharref, A., Chiaroni, A., Riche, C. & Lavergne, J.-P. (1998). Synth. Commun. 28, 2641–2651. Web of Science CrossRef CAS Google Scholar
Plattier, M. & Teisseire, P. (1974). Recherche, 19, 131–144. CAS Google Scholar
Sbai, F., Dakir, M., Auhmani, A., El Jamili, H., Akssira, M., Benharref, A., Kenz, A. & Pierrot, M. (2002). Acta Cryst. C58, o518–o520. Web of Science CSD CrossRef CAS IUCr Journals Google Scholar
Sheldrick, G. M. (2008). Acta Cryst. A64, 112–122. Web of Science CrossRef CAS IUCr Journals Google Scholar
Spek, A. L. (2009). Acta Cryst. D65, 148–155. Web of Science CrossRef CAS IUCr Journals Google Scholar
Westrip, S. P. (2010). J. Appl. Cryst. 43, 920–925. Web of Science CrossRef CAS IUCr Journals Google Scholar

This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.