Acta Crystallographica Section F

Structural Biology and Crystallization Communications

Volume 64, Part 5 (May 2008)

protein structure communications

Acta Cryst. (2008). F64, 338-342 [ doi:10.1107/S1744309108007665 ]

Structure of a putative acetyltransferase (PA1377) from Pseudomonas aeruginosa

A. M. Davies, R. Tata, F.-X. Chauviac, B. J. Sutton and P. R. Brown

Abstract: Gene PA1377 from Pseudomonas aeruginosa encodes a 177-amino-acid conserved hypothetical protein of unknown function. The structure of this protein (termed pitax) has been solved in space group I222 to 2.25 Å resolution. Pitax belongs to the GCN5-related N-acetyltransferase family and contains all four sequence motifs conserved among family members. The [beta] -strand structure in one of these motifs (motif A) is disrupted, which is believed to affect binding of the substrate that accepts the acetyl group from acetyl-CoA.

PDB reference: 2vi7

Keywords: PA1377; Pseudomonas aeruginosa; pitax; acetyltransferase.